Evidence map›Paper›PMID 24505285›Full record

Trial reportPloS one2014

Is housing quality associated with malaria incidence among young children and mosquito vector numbers? Evidence from Korogwe, Tanzania.

Jenny X Liu, Teun Bousema, Brittany Zelman, Samwel Gesase, Ramadhan Hashim, Caroline Maxwell, Daniel Chandramohan, Roly Gosling

Abstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  14. Persistently high proportions ofParasite epidemiology and control · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jenny X LiuGlobal Health Group, Global Health Sciences, University of California, San Francisco, San Francisco, California, United States of America.
Teun BousemaDepartment of Immunology & Infection, London School of Hygiene and Tropical Medicine, London, United Kingdom ; Department of Medical Microbiology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands.
Brittany ZelmanGlobal Health Group, Global Health Sciences, University of California, San Francisco, San Francisco, California, United States of America.
Samwel GesaseTanga Research Center, National Institute for Medical Research, Tanga, Tanzania.
Ramadhan HashimMwanza Interventions Trial Unit Center, National Institute for Medical Research, Mwanza, Tanzania.
Caroline MaxwellLiverpool School of Tropical Medicine, Liverpool, United Kingdom.
Daniel ChandramohanDepartment of Immunology & Infection, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Roly GoslingGlobal Health Group, Global Health Sciences, University of California, San Francisco, San Francisco, California, United States of America ; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral studies conducted in Northeast Tanzania have documented declines in malaria transmission even before interventions were scaled up. One explanation for these reductions may be the changes in socio-environmental conditions associated with economic development, and in particular improvements in housing construction.

objectiveThis analysis seeks to identify (1) risk factors for malaria incidence among young children and (2) household and environmental factors associated with mosquito vector numbers collected in the child's sleeping area. Both analyses focus on housing construction quality as a key determinant. METHODOLOGY: For 435 children enrolled in a larger trial of intermittent preventive treatment for malaria in infants in the Korogwe District in Tanga, Northeastern Tanzania, detailed information on their dwelling characteristics were collected in the last year of the trial. Principal components analysis was used to construct an index of housing structure quality and converted to quintile units for regression analysis. Univariate and multivariate random effects negative binomial regressions were used to predict risk factors for child malaria incidence and the mean total number of indoor female Anopheles gambiae and funestus mosquitoes collected per household across three occasions.

findingsBuilding materials have substantially improved in Korogwe over time. Multivariate regressions showed that residing in rural areas (versus urban) increased malaria incidence rates by over three-fold and mean indoor female A. gambiae and funestus numbers by nearly two-fold. Compared to those residing in the lowest quality houses, children residing in the highest quality houses had one-third lower malaria incidence rates, even when wealth and rural residence were controlled for. Living in the highest quality houses reduced vector numbers while having cattle near the house significantly increased them.

conclusionsResults corroborate findings from other studies that show associations between malaria incidence and housing quality; associations were concentrated amongst the highest quality houses.

Indexed as

AnophelesHousingInsect VectorsAnimalsChild, PreschoolFemaleFollow-Up StudiesHumansIncidenceInfantMalariaMaleSocioeconomic FactorsTanzania

Identifiers

PMID24505285
PMCPMC3914816

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.