ArticlePloS one2014
The origin and migration of primordial germ cells in sturgeons.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Primordial Germ Cell Development in Teleosts: Their Origin, Fate and Role in Sex Determination.Stem cell reviews and reports · 2026Review
- Conservation of Teleost Fishes: Current Status and the Role of Reproductive Technologies.Advances in experimental medicine and biology · 2026Review
- Sturgeon gut development: a unique yolk utilization strategy among vertebrates.Frontiers in cell and developmental biology · 2024Article
- MiR-34b/c play a role in early sex differentiation of Amur sturgeon, Acipenser schrenckii.Frontiers in zoology · 2022Article
- Advantages, Factors, Obstacles, Potential Solutions, and Recent Advances of Fish Germ Cell Transplantation for Aquaculture-A Practical Review.Animals : an open access journal from MDPI · 2022Review
- Efficient CRISPR Mutagenesis in Sturgeon Demonstrates Its Utility in Large, Slow-Maturing Vertebrates.Frontiers in cell and developmental biology · 2022Review
- A brief review of vertebrate sex evolution with a pledge for integrative research: towards 'Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Primordial Germ Cell Specification in Vertebrate Embryos: Phylogenetic Distribution and Conserved Molecular Features of Preformation and Induction.Frontiers in cell and developmental biology · 2021Review
- The sterlet sturgeon genome sequence and the mechanisms of segmental rediploidization.Nature ecology & evolution · 2020Article
- Full-length transcriptome sequencing and comparative transcriptomic analysis to uncover genes involved in early gametogenesis in the gonads of Amur sturgeon (Frontiers in zoology · 2020Article
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- Delivery of Iron Oxide Nanoparticles into Primordial Germ Cells in Sturgeon.Biomolecules · 2019Article
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- Polyspermy produces viable haploid/diploid mosaics in sturgeon.Biology of reproduction · 2018Article
- Elimination of primordial germ cells in sturgeon embryos by ultraviolet irradiation.Biology of reproduction · 2018Article
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- Multiplicity of Buc copies in Atlantic salmon contrasts with loss of the germ cell determinant in primates, rodents and axolotl.BMC evolutionary biology · 2016Article
- Finding their way: themes in germ cell migration.Current opinion in cell biology · 2016Review
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- Leapfrogging: primordial germ cell transplantation permits recovery of CRISPR/Cas9-induced mutations in essential genes.Development (Cambridge, England) · 2016Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primordial germ cells (PGCs) arise elsewhere in the embryo and migrate into developing gonadal ridges during embryonic development. In several model animals, formation and migration patterns of PGCs have been studied, and it is known that these patterns vary. Sturgeons (genus Acipenser) have great potential for comparative and evolutionary studies of development. Sturgeons belong to the super class Actinoptergii, and their developmental pattern is similar to that of amphibians, although their phylogenetic position is an out-group to teleost fishes. Here, we reveal an injection technique for sturgeon eggs allowing visualization of germplasm and PGCs. Using this technique, we demonstrate that the PGCs are generated at the vegetal pole of the egg and they migrate on the yolky cell mass toward the gonadal ridge. We also provide evidence showing that PGCs are specified by inheritance of maternally supplied germplasm. Furthermore, we demonstrate that the migratory mechanism is well-conserved between sturgeon and other remotely related teleosts, such as goldfish, by a single PGCs transplantation (SPT) assay. The mode of PGCs specification in sturgeon is similar to that of anurans, but the migration pattern resembles that of teleosts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.