Evidence map›Paper›PMID 24505214›Full record

ArticleTropical medicine and health2013

Prevalence of HIV and Disease Outcomes on the Medical and Surgical Wards at Kamuzu Central Hospital, Lilongwe, Malawi.

Claire E Kendig, Denise J McCulloch, Nora E Rosenberg, Jonathan C Samuel, Charles Mabedi, Carol G Shores, Mina C Hosseinipour, Mitch Matoga, Anthony G Charles

Open access · bronzeAbstract read
In one paragraph

Article in Tropical medicine and health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Policy to practice: impact of GeneXpert MTB/RIF implementation on the TB spectrum of care in Lilongwe, Malawi.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2016
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Claire E KendigUNC Project, Lilongwe, Malawi.
Denise J McCullochUNC Project, Lilongwe, Malawi.
Nora E RosenbergUNC Project, Lilongwe, Malawi.
Jonathan C SamuelUniversity of North Carolina Chapel Hill, Department of Surgery, Division of Trauma and Critical Care Surgery.
Charles MabediKamuzu Central Hospital, Department of Surgery.
Carol G ShoresUniversity of North Carolina Chapel Hill, Department of Otolaryngology/Head & Neck Surgery.
Mina C HosseinipourUNC Project, Lilongwe, Malawi ; University of North Carolina Chapel Hill, Department of Medicine, Division of Infectious Diseases.
Mitch MatogaUNC Project, Lilongwe, Malawi ; Kamuzu Central Hospital, Department of Medicine.
Anthony G CharlesUniversity of North Carolina Chapel Hill, Department of Surgery, Division of Trauma and Critical Care Surgery.
University of North Carolina at Chapel Hill · USKamuzu Central Hospital · MW

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Fogarty Global Health Fellows Coordinating CenterR25TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHI, BENJAMIN H. · 2012 to 2016
$6.9M
Best Management of Sigmoid Volvulus: a Prospective Randomized TrialK01TW009486 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SAMUEL, JONATHAN CHARLES · 2012 to 2013
$234k
FIC NIH HHS K01 TW009486FIC NIH HHS R25 TW009340NIAID NIH HHS P30 AI050410
6 · The paper itself

Abstract

introductionThe World Health Organization (WHO) recommends HIV Counseling and Testing (HCT) in a range of clinical settings. We describe the characteristics of patients diagnosed with HIV on the medical and surgical wards at a tertiary care hospital in Malawi.

methodsUnder the universal opt-out HCT protocol we characterized the number of new HIV/AIDS infections and associated clinical features among hospitalized surgical and medical patients diagnosed during the course of admission.

resultsAll 2985 and 3959 medical and surgical patients, respectively, admitted between April 2012 and January 2013 were screened for HCT. 62% and 89% of medical and surgical patients, respectively, had an unknown status on admission and qualified for testing. Of the patients with an unknown status, a new HIV diagnosis was made in 20% and 7% of medical and surgical patients, respectively. Of the newly diagnosed patients with a CD4 count recorded, 91% and 67% of medical and surgical patients, respectively, had a count less than 350, qualifying for ART by Malawi ART guidelines. Newly HIV-diagnosed medical and surgical patients had an inpatient mortality of 20% and 2%, respectively. DISCUSSION: While newly diagnosed HIV-positive medical patients had high inpatient mortality and higher rates of WHO stage 3 or 4 conditions, surgical patients presented with less advanced HIV, though still meeting ART initiation guidelines. The medical inpatient wards are an obvious choice for implementing voluntary counseling and testing (VCT), but surgical patients present with less advanced disease and starting treatment in this group could result in more years of life gained.

Indexed as

HIV counseling and testinginpatientmedicinesub-Saharan Africasurgery

Identifiers

PMID24505214
PMCPMC3883455
OpenAlexW2067939214

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.