ArticleSurgery today2014
Impact of the post/preoperative serum CEA ratio on the survival of patients with rectal cancer.
Article in Surgery today, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 23 citations in OpenAlex.
- Graphene Oxide (GO) and Gold Nanoparticles (AuNP) Facilitated Electrochemical Biosensing for Lung Cancer Diagnosis.Diagnostics (Basel, Switzerland) · 2026Review
- Prognostic significance of CEA reduction rate in patients with abnormally high preoperative CEA levels who underwent surgery for lung cancer.Journal of cardiothoracic surgery · 2024Article
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- A machine learning-based model for predicting distant metastasis in patients with rectal cancer.Frontiers in oncology · 2023Article
- Can Elevated Pretreatment Serum Carcinoembryonic Antigen Levels Serve as a Potential Biomarker Guiding Adjuvant Chemotherapy in Rectal Cancer Patients With ypTis-3N0 After Neoadjuvant Radiotherapy and Surgery?Frontiers in oncology · 2021Article
- Association between Primary Perioperative CEA Ratio, Tumor Site, and Overall Survival in Patients with Colorectal Cancer.Journal of clinical medicine · 2020Article
- Clinical Significances of Positive Postoperative Serum CEA and Post-preoperative CEA Increment in Stage II and III Colorectal Cancer: A Multicenter Retrospective Study.Frontiers in oncology · 2020Article
- Prognostic impact of preoperatively elevated and postoperatively normalized carcinoembryonic antigen levels following curative resection of stage I-III rectal cancer.Cancer medicine · 2020Article
- Development and validation of nomogram combining serum biomarker for predicting survival in patients with resected rectal cancer.Bioscience reports · 2019Article
- Genome-wide long non-coding RNAs identified a panel of novel plasma biomarkers for gastric cancer diagnosis.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2019Article
- The prognostic value of the postoperative serum CEA levels/preoperative serum CEA levels ratio in colorectal cancer patients with high preoperative serum CEA levels.Cancer management and research · 2019Article
- Perioperative Serum Carcinoembryonic Antigen Ratio Is a Prognostic Indicator in Patients With Stage II Colorectal Cancer.Annals of coloproctology · 2018Article
- Pre-operative to post-operative serum carcinoembryonic antigen ratio is a prognostic indicator in colorectal cancer.Oncotarget · 2017Article
- Changes of Microrna Levels in Plasma of Patients with Rectal Cancer during Chemoradiotherapy.International journal of molecular sciences · 2017Article
- Prognostic value of parameters derived from white blood cell and differential counts in patients receiving palliative radiotherapy.Molecular and clinical oncology · 2016Article
- LncRNA-RMRP promotes carcinogenesis by acting as a miR-206 sponge and is used as a novel biomarker for gastric cancer.Oncotarget · 2016Article
- Clinicopathologic features and oncologic outcomes of colorectal cancer patients with extremely high carcinoembryonic antigen.International journal of colorectal disease · 2015Article
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study demonstrated the usefulness of the post/preoperative serum carcinoembryonic antigen (CEA) ratio as a predictor of survival after surgery for stage III rectal cancer patients.
methodsOne hundred and four patients with stage III rectal cancer who underwent surgery between 1991 and 2000 were enrolled. The ratio of the postoperative serum CEA value divided by the preoperative serum CEA value was defined as post/preoperative serum CEA ratio, and the patients were separated into two groups: post/preoperative serum CEA ratio ≤ 1 (n = 86) and >1 (n = 18).
resultsThe multivariate analyses demonstrated that the intraoperative blood loss, lack of a sphincter-saving procedure and a post/preoperative serum CEA ratio >1 were independent factors predicting a poor prognosis for the overall and disease-free survival. The overall and disease-free survival rates among patients with a high preoperative serum CEA level (>5 ng/ml) or patients with a high postoperative serum CEA (>5 ng/ml) were longer in patients with a post/preoperative serum CEA ratio ≤ 1, in comparison to those with a post/preoperative serum CEA ratio >1. Liver metastasis was observed more frequently in patients with a post/preoperative serum CEA ratio >1.
conclusionsThe post/preoperative serum CEA ratio may be a predictor of the prognosis after surgery for stage III rectal cancer patients.
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