ArticleHuman genetics2014
Recollections of a scientific journey published in human genetics: from chromosome territories to interphase cytogenetics and comparative genome hybridization.
Article in Human genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- Recent advances and future perspectives in vector-omics.Current opinion in insect science · 2020Review
- Chromatin Structure and Function in Mosquitoes.Frontiers in genetics · 2020Review
- Chromatin topology, condensates and gene regulation: shifting paradigms or just a phase?Development (Cambridge, England) · 2019Review
- Small chromosomal regions position themselves autonomously according to their chromatin class.Genome research · 2017Article
- Nucleolus association of chromosomal domains is largely maintained in cellular senescence despite massive nuclear reorganisation.PloS one · 2017Article
- Heterochromatin, histone modifications, and nuclear architecture in disease vectors.Current opinion in insect science · 2015Article
- Current theoretical models fail to predict the topological complexity of the human genome.Frontiers in molecular biosciences · 2015Article
- Human genetics' 50th anniversary issue.Human genetics · 2014Article
- Special issue: Nuclear architecture and chromatin motions in the DNA damage response.Mutation researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In line with the intentions of an issue celebrating the 50th anniversary of Human Genetics, we focus on a series of frequently cited studies published in this journal during the 1980s and 1990s. These studies have contributed to the rise of molecular cytogenetics. They yielded evidence that chromosomes occupy distinct territories in the mammalian cell nucleus, first obtained with laser-UV-microbeam experiments and thereafter with chromosome painting, and contributed to the development of interphase cytogenetics and comparative genome hybridization. We provide a personal account of experimental concepts, which were developed by us and others, and describe some of the unforeseeable turns and obstacles, which we had to overcome on the way towards an experimental realization. We conclude with a perspective on current developments and goals of molecular cytogenetics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.