ArticleMycotoxin research2014
The major volatile compound 2-phenylethanol from the biocontrol yeast, Pichia anomala, inhibits growth and expression of aflatoxin biosynthetic genes of Aspergillus flavus.
Article in Mycotoxin research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
75 citing papers in PubMed, 178 citations in OpenAlex.
- Wickerhamomyces anomalus as a biocontrol agent against Aspergillus clavatus and patulin in apples.Scientific reports · 2026Article
- Pathogen-induced modulation of the volatile metabolome of Hanseniaspora uvarum LE-1 and its role in post-harvest disease suppression.World journal of microbiology & biotechnology · 2026Article
- Extracellular Metabolites fromMicroorganisms · 2026Article
- Air volume not spray concentration determines in vivo efficacy of volatile organic compounds against Plasmopara viticola.Scientific reports · 2026Article
- Microbial Volatiles from Human Skin and Floral Nectar: Insufficiently Understood Adult Feeding Cues To Improve Odor-Based Traps for Aedes Vector Control.Journal of chemical ecology · 2025Review
- Impact of kefir yeasts on Fusarium graminearum growth and production of deoxynivalenol.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- A Novel Plate Compartment-Confrontation Method Discovered That Volatile Organic Compounds Produced byJournal of fungi (Basel, Switzerland) · 2025Article
- Profiles of Killer Systems and Volatile Organic Compounds of Rowanberry and Rosehip-Inhabiting Yeasts Substantiate Implications for Biocontrol.Foods (Basel, Switzerland) · 2025Article
- Characterization and biocontrol potential ofHeliyon · 2024Article
- Dual Role of Yeasts and Filamentous Fungi in Fermented Sausages.Foods (Basel, Switzerland) · 2024Review
- Microbial Volatile Organic Compounds: Insights into Plant Defense.Plants (Basel, Switzerland) · 2024Review
- A New Benzaldehyde Derivative Exhibits Antiaflatoxigenic Activity againstJournal of fungi (Basel, Switzerland) · 2023Article
- Volatile Organic Compounds ofFoods (Basel, Switzerland) · 2023Article
- Nutritional Profile and Ecological Interactions of Yeast Symbionts Associated with North American Spruce Beetle (Dendroctonus rufipennis).Microbial ecology · 2023Article
- Protection of postharvest grains from fungal spoilage by biogenic volatiles.Applied microbiology and biotechnology · 2023Review
- Biocontrol and Probiotic Function of Non-Microorganisms · 2023Review
- Characterization of kefir yeasts with antifungal capacity against Aspergillus species.International microbiology : the official journal of the Spanish Society for Microbiology · 2023Article
- Mycotoxin Contamination Status of Cereals in China and Potential Microbial Decontamination Methods.Metabolites · 2023Review
- Antifungal Activity of Volatile Components from Ceratocystis fimbriata and Its Potential Biocontrol Mechanism on Alternaria alternata in Postharvest Cherry Tomato Fruit.Microbiology spectrum · 2023Article
- A carnivorous mushroom paralyzes and kills nematodes via a volatile ketone.Science advances · 2023Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aspergillus flavus is a ubiquitous saprophyte that is able to produce the most potent natural carcinogenic compound known as aflatoxin B1 (AFB1). This toxin frequently contaminates crops including corn, cotton, peanuts, and tree nuts causing substantial economic loss worldwide. Consequently, more than 100 countries have strict regulations limiting AFB1 in foodstuffs and feedstuffs. Plants and microbes are able to produce volatile compounds that act as a defense mechanism against other organisms. Pichia anomala strain WRL-076 is a biocontrol yeast currently being tested to reduce AF contamination of tree nuts in California. We used the SPME-GC/MS analysis and identified the major volatile compound produced by this strain to be 2-phenylethanol (2-PE). It inhibited spore germination and AF production of A. flavus. Inhibition of AF formation by 2-PE was correlated with significant down regulation of clustering AF biosynthesis genes as evidenced by several to greater than 10,000-fold decrease in gene expression. In a time-course analysis we found that 2-PE also altered the expression patterns of chromatin modifying genes, MYST1, MYST2, MYST3, gcn5, hdaA and rpdA. The biocontrol capacity of P. anomala can be attributed to the production of 2-PE, which affects spore germination, growth, toxin production, and gene expression in A. flavus.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.