Evidence map›Paper›PMID 24504066›Full record

ArticleInternational urogynecology journal2014

What is clinically relevant prolapse? An attempt at defining cutoffs for the clinical assessment of pelvic organ descent.

H P Dietz, K P Mann

Abstract read
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In one paragraph

Article in International urogynecology journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
9.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 95 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. [Deep learning models based on fused ultrasound images for the assessment of cystocele in women].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
    Article
  5. Observational
  6. Observational
  7. Review
  8. Measuring Pelvic Organ Prolapse: An Evolution.International urogynecology journal · 2024
    Review
  9. Review
  10. Article
  11. Is urethral pressure associated with parity and delivery mode?International urogynecology journal · 2022
    Article
  12. Article
  13. Is vaginal laxity an early symptom of pelvic organ prolapse?International urogynecology journal · 2022
    Observational
  14. Observational
  15. 2D ultrasound diagnosis of middle compartment prolapse: a multicenter study.Quantitative imaging in medicine and surgery · 2022
    Article
  16. Article
  17. Review
  18. Observational
  19. Article
  20. Is vaginal flatus related to pelvic floor functional anatomy?International urogynecology journal · 2020
    Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

H P DietzSydney Medical School Nepean, Nepean Hospital, Penrith, NSW, 2750, Australia, hpdietz@bigpond.com.
K P Mann
National Health and Medical Research Council · AUUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisThis study was undertaken to investigate the relationship between symptoms of prolapse and International Continence Society Pelvic Organ Prolapse Quantification (ICS POP-Q) measurements in order to establish optimal cutoffs for predicting prolapse symptoms using receiver operator characteristic (ROC) statistics.

methodsThis was a retrospective study using 764 archived data sets of patients seen for symptoms of lower urinary tract and pelvic floor dysfunction between March 2011 and November 2012. Main outcome measure was symptoms of prolapse. Explanatory parameters were Ba, C, and Bp as defined by the ICS POP-Q. Patient age, body mass index (BMI), previous hysterectomy or incontinence/prolapse surgery, and vaginal parity were tested for a confounding effect on the relationship between ICS POP-Q measurements and symptoms of prolapse.

resultsOptimal cutoffs for predicting prolapse symptoms were defined as follows: Ba = -0.5 (sensitivity 69 %, specificity 71 %), C =-5 (sensitivity 67 %, specificity 64 %), Bp = -0.5 (sensitivity 63 %, specificity 62 %). ROC statistics resulted in an area under the curve of 0.768 for Ba [confidence interval (CI) 0.729-0.807), for C of 0.724 (CI 0.672-0.776), and for Bp of 0.686 (CI 0.639-0.733).

conclusionOur findings suggest that the ICS POP-Q staging system requires revision. Prolapse of the anterior and posterior vaginal wall of < -1 should probably be regarded as normal. On the other hand, stage 1 uterine prolapse as currently defined seems highly relevant.

Indexed as

AdultAgedAged, 80 and overFemaleHumansMiddle AgedPelvic Organ ProlapseRetrospective StudiesROC CurveSeverity of Illness IndexYoung Adult

Identifiers

PMID24504066
OpenAlexW2059160102

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.