ArticlePloS one2014
Abdominal aortic intimal flap motion characterization in acute aortic dissection: assessed with retrospective ECG-gated thoracoabdominal aorta dual-source CT angiography.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 38 citations in OpenAlex.
- Spectral Computed Tomography for the Detection and Characterization of Communications Between the True and the False Lumen in Aortic Dissections.Investigative radiology · 2026Article
- A Fluid-Structure Interaction Computational Study of Residual Aortic Dissection to Investigate the Influence of Mechanical Behaviour of Wall and Flap on Flows.International journal for numerical methods in biomedical engineering · 2025Article
- Impact of Residual Intimal Flap Displacement Post-TEVAR on TBAD Haemodynamics in Compliant, Patient-specific CFD Simulations Informed by MRI.Annals of biomedical engineering · 2025Article
- Mechanisms of aortic dissection: From pathological changes to experimental andProgress in materials science · 2025Article
- Predicting Aneurysmal Degeneration in Uncomplicated Residual Type B Aortic Dissection.Bioengineering (Basel, Switzerland) · 2024Article
- Significance of systolic-phase imaging on full-phase ECG-gated CT angiography to detect intimal tears in aortic dissection.Heart and vessels · 2022Article
- AnFrontiers in cardiovascular medicine · 2022Article
- A novel MRI-based data fusion methodology for efficient, personalised, compliant simulations of aortic haemodynamics.Journal of biomechanics · 2021Article
- Detection of the intimal tear in aortic dissection and ulcer-like projection in intramural hematoma: usefulness of full-phase retrospective ECG-gated CT angiography.Japanese journal of radiology · 2020Article
- Optimal phase analysis of electrocardiogram-gated computed tomography angiography in patients with Stanford type A acute aortic dissection.European journal of radiology open · 2020Article
- High intimal flap mobility assessed by intravascular ultrasound is associated with better short-term results after TEVAR in chronic aortic dissection.Scientific reports · 2019Article
- Type A aortic dissection in pregnant patients with fibrillin-1 gene mutations: Two case reports and a literature review.Experimental and therapeutic medicine · 2018Article
- Role of Pulse Pressure and Geometry of Primary Entry Tear in Acute Type B Dissection Propagation.Annals of biomedical engineering · 2017Article
- Aortic dissection simulation models for clinical support: fluid-structure interaction vs. rigid wall models.Biomedical engineering online · 2015Article
- CT angiography in the diagnosis of cardiovascular disease: a transformation in cardiovascular CT practice.Quantitative imaging in medicine and surgery · 2014Review
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13 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the feasibility of dose-modulated retrospective ECG-gated thoracoabdominal aorta CT angiography (CTA) assessing abdominal aortic intimal flap motion and investigate the motion characteristics of intimal flap in acute aortic dissection (AAD). MATERIALS AND
methods49 patients who had thoracoabdominal aorta retrospective ECG-gated CTA scan were enrolled. 20 datasets were reconstructed in 5% steps between 0 and 95% of the R-R interval in each case. The aortic intimal flap motion was assessed by measuring the short axis diameters of the true lumen and false lumen 2 cm above of celiac trunk ostium in different R-R intervals. Intimal flap motion and configuration was assessed by two independent observers.
resultsIn these 49 patients, 37 had AAD, 7 had intramural hematoma, and 5 had negative result for acute aortic disorder. 620 datasets of 31 patients who showed double lumens in abdominal aorta were enrolled in evaluating intimal flap motion. The maximum and minimum true lumen diameter were 12.2 ± 4.1 mm (range 2.6 ∼ 17.4) and 6.7 ± 4.1 mm (range 0 ∼ 15.3) respectively. The range of intimal flap motion in all patients was 5.5 ± 2.6 mm (range 1.8 ∼ 10.2). The extent of maximum true lumen diameter decreased during a cardiac cycle was 49.5% ± 23.5% (range 12% ∼ 100%). The maximum motion phase of true lumen diameter was in systolic phase (5% ∼ 40% of R-R interval). Maximum and minimum intimal flap motion was at 15% and 75% of the R-R interval respectively. Intimal flap configuration had correlation with the phase of cardiac cycle.
conclusionsAbdominal intimal flap position and configuration varied greatly during a cardiac cycle. Retrospective ECG-gated thoracoabdominal aorta CTA can reflect the actual status of the true lumen and provide more information about true lumen collapse. This information may be helpful to diagnosis and differential diagnosis of dynamic abstraction.
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