Evidence map›Paper›PMID 24503596›Full record

ArticlePloS one2014

Modified Mediterranean diet score and cardiovascular risk in a North American working population.

Justin Yang, Andrea Farioli, Maria Korre, Stefanos N Kales

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02941757 (Feeding America's Bravest), which is not on this map. Cited by 51 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 2 pooled it
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02941757 nacompletednot on this mapstarted 2016, after this paper: background citation

Feeding America's Bravest: Mediterranean Diet-Based Interventions to Change Firefighters' Eating Habits and Improve Cardiovascular Risk Profiles

TypeinterventionalSponsorHarvard School of Public Health (HSPH)Ran2016 to 2019Enrolled486ConditionsDiet, Mediterranean, Health Behavior, Program Sustainability, Program EffectivenessArmsMediterranean diet Intervention
3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 2 syntheses or guidelines pooled it, 98 citations in OpenAlex.

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  17. Frontiers in endocrinology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Justin YangDepartment of Environmental Health, Environmental & Occupational Medicine & Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America ; The Cambridge Health Alliance, Harvard Medical School, Cambridge, Massachusetts, United States of America.
Andrea FarioliDepartment of Environmental Health, Environmental & Occupational Medicine & Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America ; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
Maria KorreDepartment of Environmental Health, Environmental & Occupational Medicine & Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America ; The Cambridge Health Alliance, Harvard Medical School, Cambridge, Massachusetts, United States of America.
Stefanos N KalesDepartment of Environmental Health, Environmental & Occupational Medicine & Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America ; The Cambridge Health Alliance, Harvard Medical School, Cambridge, Massachusetts, United States of America.
Harvard University · USUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGreater adherence to a Mediterranean diet is linked to lower risk for cardiovascular morbidity/mortality in studies of Mediterranean cohorts, older subjects, and/or those with existing health conditions. No studies have examined the effects of this dietary pattern in younger working populations in the United States. We investigated the effects of Mediterranean diet adherence on cardiovascular disease (CVD) biomarkers, metabolic syndrome and body composition in an occupationally active, non-Mediterranean cohort.

methodsA cross-sectional study in a cohort of 780 career male firefighters, ages 18 years or older, from the United States Midwest. No dietary intervention was performed. A modified Mediterranean diet score (mMDS) was developed for assessment of adherence to a Mediterranean dietary pattern from a previously administered life-style questionnaire that examined pre-existing dietary habits. Clinical data from fire department medical examinations were extracted and analyzed.

resultsObese subjects had significantly lower mMDS, and they reported greater fast/take-out food consumption (p<0.001) and intake of sweetened drinks during meals (p = 0.002). After multivariate adjustment, higher mMDS was inversely related to risk of weight gain over the past 5 years (odds ratio [OR]: 0.57, 95% confidence interval [CI]: 0.39-0.84, p for trend across score quartiles: 0.01); as well as the presence of metabolic syndrome components (OR: 0.65, 95% CI: 0.44-0.94, p for trend across score quartiles: 0.04). Higher HDL-cholesterol (p = 0.008) and lower LDL-cholesterol (p = 0.04) were observed in those with higher mMDS in linear regression after multivariate adjustment for age, BMI and physical activity.

conclusionsIn a cohort of young and active US adults, greater adherence to a Mediterranean-style dietary pattern had significant inverse associations with metabolic syndrome, LDL-cholesterol and reported weight gain, and was significantly and independently associated with higher HDL-cholesterol. Our results support the potential effectiveness of this diet in young, non-Mediterranean working cohorts, and justify future intervention studies.

Indexed as

Diet, MediterraneanEmploymentAdultAnthropometryCardiovascular DiseasesHumansLinear ModelsMaleMetabolic SyndromeNorth AmericaRisk FactorsWorkforce

Identifiers

PMID24503596
PMCPMC3913651
OpenAlexW2151549560

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.