Evidence map›Paper›PMID 24503298›Full record

ArticleBMJ open2014

A cross-sectional study of Mycoplasma genitalium infection and correlates in women undergoing population-based screening or clinic-based testing for Chlamydia infection in London.

H F Svenstrup, S S Dave, C Carder, P Grant, S Morris-Jones, M Kidd, J M Stephenson

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Prevalence ofSexually transmitted infections · 2018
    Pooled it
  2. Article
  3. Article
  4. Epidemiology and infection · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Assessing the Need for Routine Screening forInternational journal of preventive medicine · 2017
    Article
  11. Mycoplasma genitalium: An Overlooked Sexually Transmitted Pathogen in Women?Infectious diseases in obstetrics and gynecology · 2016
    Review
  12. Article
  13. Article
  14. Molecular methods in the laboratory diagnosis of sexually transmitted infections.Indian journal of sexually transmitted diseases and AIDS
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

H F SvenstrupResearch Department of Reproductive Medicine, Institute for Women's Health, University College London, UK.
S S Dave
C Carder
P Grant
S Morris-Jones
M Kidd
J M Stephenson
University College London · GB

Funding

Department of Health PB-PG-0906-11154Department of Health RP-DG-1209-10029Medical Research Council MR/K006584/1
6 · The paper itself

Abstract

objectiveTo determine Mycoplasma genitalium infection and correlates among young women undergoing population-based screening or clinic-based testing for Chlamydia infection.

designCross-sectional study.

settingNational Chlamydia Screening Programme (NCSP) and two London sexually transmitted infection (STI) clinics.

participants2441 women aged 15-64 years who participated in the NCSP and 2172 women who attended two London STI clinics over a 4-month period in 2009. OUTCOME MEASURES: (1) M genitalium prevalence in defined populations (%). (2) Age-adjusted ORs (aORs) for correlates of M genitalium infection.

resultsThe overall frequency of M genitalium and Chlamydia trachomatis was 3% and 5.4%, respectively. Co-infection was relatively uncommon (0.5% of all women); however 9% of women with C trachomatis also had M genitalium infection. M genitalium was more frequently detected in swab than urine samples (3.9 vs 1.3%, p<0.001) with a significantly higher mean bacterial load (p ≤ 0.001). Among NCSP participants, M genitalium was significantly more likely to be diagnosed in women of black/black British ethnicity (aOR 2.3, 95% CI 1.2 to 4.5, p=0.01). M genitalium and C trachomatis and were both significantly associated with multiple sexual partners in the past year (aOR 2.4, 95% CI 1.3 to 4.4, p=0.01 and aOR 2.0, 95% CI 1.4 to 2.8, p<0.01). Among STI clinic attendees, M genitalium was more common in women who were less than 25 years in age.

conclusionsM genitalium is a relatively common infection among young women in London. It is significantly more likely to be detected in vulvovaginal swabs than in urine samples. Co-infection with Chlamydia is uncommon. The clinical effectiveness of testing and treatment strategies for M genitalium needs further investigation.

Indexed as

Mass ScreeningAdolescentAdultChlamydia InfectionsCoinfectionCross-Sectional StudiesFemaleHumansLondonMiddle AgedMycoplasma genitaliumMycoplasma InfectionsPrevalenceRisk FactorsSexual PartnersEpidemiologyGenitourinary MedicineMicrobiology

Identifiers

PMID24503298
PMCPMC3918997
OpenAlexW2025341181

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.