Evidence map›Paper›PMID 24503132›Full record

ReviewGastroenterology2014

Diet and the intestinal microbiome: associations, functions, and implications for health and disease.

Lindsey G Albenberg, Gary D Wu

2 registry-linked trialsOpen access · greenAbstract readReview
In one paragraph

Review in Gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 287 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
287citing papers in PubMed, 3 pooled it
19.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04398550 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Specific Carbohydrate Diet vs. Mediterranean Diet Therapy in Ulcerative Colitis - A Clinical Trial

TypeinterventionalSponsorMassachusetts General HospitalRan2020 to 2023Enrolled50ConditionsUlcerative ColitisArmsSpecific Carbohydrate Diet, Mediterranean Diet
NCT07742319 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Effect of Soil Biodiversity on Human Gut Microbiome: a Process Pilot Study (The HUMANITAS Study)

TypeinterventionalSponsorLeiden University Medical CenterRan2026 to 2026Enrolled10ConditionsPilot StudyArmsLow diversity vegetable smoothie, High diversity vegetable smoothie
3 · Its place in the literature

Who cites it

287 citing papers in PubMed, 3 syntheses or guidelines pooled it, 598 citations in OpenAlex.

  1. Pooled it
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  3. Drugs for preventing lung cancer in healthy people.The Cochrane database of systematic reviews · 2020
    Pooled it
  4. Trial
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  10. Review
  11. Article
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  15. The Role of Selected Bacteria in Breast Cancer Initiation and Development.International journal of molecular sciences · 2026
    Review
  16. Article
  17. Review
  18. Association between an anti-inflammatory low-carbohydrate diet and gingivitis in women with obesity.Canadian journal of dental hygiene : CJDH = Journal canadien de l'hygiene dentaire : JCHD · 2026
    Article
  19. Article
  20. Article

227 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Lindsey G AlbenbergDivision of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Gary D WuDivision of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: gdwu@mail.med.upenn.edu.
Children's Hospital of Philadelphia · USUniversity of Pennsylvania · US

Funding

Diet, Genetic Factors, and the Gut Microbiome in Crohn's DiseaseUH2DK083981 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI BUSHMAN, FREDERIC D, LEWIS, JAMES D · 2009 to 2010
$2.3M
Diet, Genetic Factors, and the Gut Microbiome in Crohn's DiseaseUH3DK083981 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI BUSHMAN, FREDERIC D, LEWIS, JAMES D · 2011 to 2012
$1.7M
Host-microbial interactions in the gut oxygen equilibriumR01GM103591 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI WU, GARY D. · 2013 to 2016
$1.3M
Regulation of Host Nitrogen Balance by the Gut MicrobiomeR01DK089472 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI WU, GARY D. · 2010 to 2012
$1.1M
NIDDK NIH HHS R01 DK089472NIDDK NIH HHS UH2/3 DK083981NIDDK NIH HHS UH2 DK083981NIDDK NIH HHS UH3 DK083981NIGMS NIH HHS R01 GM103591
6 · The paper itself

Abstract

The mutual relationship between the intestinal microbiota and its mammalian host is influenced by diet. Consumption of various nutrients affects the structure of the microbial community and provides substrates for microbial metabolism. The microbiota can produce small molecules that are absorbed by the host and affect many important physiological processes. Age-dependent and societal differences in the intestinal microbiota could result from differences in diet. Examples include differences in the intestinal microbiota of breastfed vs formula-fed infants or differences in microbial richness in people who consume an agrarian plant-based vs a Western diet, which is high in meat and fat. We review how diet affects the structure and metabolome of the human intestinal microbiome and may contribute to health or the pathogenesis of disorders such as coronary vascular disease and inflammatory bowel disease.

Indexed as

DietHealth StatusMicrobiotaAnimalsBacteriaDysbiosisGastrointestinal DiseasesHost-Pathogen InteractionsHumansIntestinal MucosaIntestinesMetabolomeMetabolomicsDietInflammationIntestineMicrobiota

Identifiers

PMID24503132
PMCPMC4216184
OpenAlexW2067791097

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.