Evidence map›Paper›PMID 24502856›Full record

Trial reportJournal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale2014

CO(2) laser versus cold steel margin analysis following endoscopic excision of glottic cancer.

Fawaz M Makki, Matthew H Rigby, Martin Bullock, Timothy Brown, Robert D Hart, Jonathan Trites, Michael L Hinni, S Mark Taylor

Open access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Injection laryngoplasty during transoral laser microsurgery for early glottic cancer: a randomized controlled trial.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2022
    Trial
  2. Outcomes of Surgical Bed Versus Tumor Margins in Trans-Oral Resection of Early Glottic Cancer.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
  3. Article
  4. Review
  5. Phonosurgery: A review of current methodologies.World journal of otorhinolaryngology - head and neck surgery · 2021
    Review
  6. Long Term Oncological Results of Transoral Laser Microsurgery for Early and Moderately Advanced Glottic Carcinoma in Primary and Salvage Settings.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2018
    Article
  7. Is There a Change in the Treatment of T1 Glottic Cancer After COTurkish archives of otorhinolaryngology · 2018
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Fawaz M Makki
Matthew H Rigby
Martin Bullock
Timothy Brown
Robert D Hart
Jonathan Trites
Michael L Hinni
S Mark TaylorDepartment of Surgery, Division of Otolaryngology Head & Neck Surgery, Dalhousie University, Halifax, Nova Scotia, Canada. smtaylorwashu@yahoo.com.
Dalhousie University · CAMayo Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the suitability of CO2 laser with steel instruments for margin excision in transoral laser microsurgery.

methodsProspective randomized blinded study. Patients with glottic cancer undergoing laser resection were randomized to margin excision by either steel instruments or CO2 laser. Margins were analyzed for size, interpretability and degree of artifact by a pathologist who was blinded to technique.

results45 patients were enrolled in the study with 226 total margins taken. 39 margins taken by laser had marked artifact and 0 were uninterpretable. 20 margins taken by steel instruments had marked artifact, and 2 were uninterpretable. Controlling for margin size, the laser technique was associated with increasing degrees of margin artifact (p = 0.210), but there was no difference in crude rates of uninterpretability (p = 0.24).

conclusionLaser margin excision is associated with a greater degree of artifact than steel instrument excision, but was not associated with higher rate of uninterpretability.

Indexed as

SteelSurgical InstrumentsAdultAgedAged, 80 and overArtifactsCarcinoma, Squamous CellDouble-Blind MethodFemaleGlottisHumansLaryngeal NeoplasmsLaryngoscopyLarynxLasers, GasLogistic ModelsSteel

Identifiers

PMID24502856
PMCPMC3927765
OpenAlexW2120083214

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.