ArticleThe Journal of organic chemistry2014
NDI and DAN DNA: nucleic acid-directed assembly of NDI and DAN.
Article in The Journal of organic chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Achiral guest-mediated modulation of circularly polarized luminescence in chiral charge-transfer cocrystals.Chemical science · 2026Article
- Sculpting photoproducts with DNA origami.Chem · 2024Article
- Tailored Tolane-Perfluorotolane Assembly as Supramolecular Base Pair Replacement in DNA.Angewandte Chemie (International ed. in English) · 2023Article
- Anion-π catalysis on carbon allotropes.Beilstein journal of organic chemistry · 2023Review
- A terminal functionalization strategy reveals unusual binding abilities of anti-thrombin anticoagulant aptamers.Molecular therapy. Nucleic acids · 2022Article
- Exploiting the interactions of aromatic units for folding and assembly in aqueous environments.Chemical communications (Cambridge, England) · 2016Article
- Influence of perylenediimide-pyrene supramolecular interactions on the stability of DNA-based hybrids: Importance of electrostatic complementarity.Beilstein journal of organic chemistry · 2014Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Two novel DNA base surrogate phosphoramidites 1 and 2, based upon relatively electron-rich 1,5-dialkoxynaphthalene (DAN) and relatively electron-deficient 1,4,5,8-naphthalenetetracarboxylic diimide (NDI), respectively, were designed, synthesized, and incorporated into DNA oligonucleotide strands. The DAN and NDI artificial DNA bases were inserted within a three-base-pair region within the interior of a 12-mer oligonucleotide duplex in various sequential arrangements and investigated with CD spectroscopy and UV melting curve analysis. The CD spectra of the modified duplexes indicated B-form DNA topology. Melting curve analyses revealed trends in DNA duplex stability that correlate with the known association of DAN and NDI moieties in aqueous solution as well as the known favorable interactions between NDI and natural DNA base pairs. This demonstrates that DNA duplex stability and specificity can be driven by the electrostatic complementarity between DAN and NDI. In the most favorable case, an NDI-DAN-NDI arrangement in the middle of the DNA duplex was found to be approximately as stabilizing as three A-T base pairs.
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Registered trials
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