Evidence map›Paper›PMID 24501546›Full record

ArticleClinical, cosmetic and investigational dentistry2014

Evaluation of the stability and antimicrobial activity of an ethanolic extract of Libidibia ferrea.

Raquel de Oliveira Marreiro, Maria Fulgência Costa Lima Bandeira, Tatiane Pereira de Souza, Mailza Costa de Almeida, Katiana Bendaham, Gisely Naura Venâncio, Isis Costa Rodrigues, Cristiane Nagai Coelho, Patrícia Sâmea Lêdo Lima Milério, Glauber Palma de Oliveira and 1 more

Open access · goldAbstract read
In one paragraph

Article in Clinical, cosmetic and investigational dentistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Efficacy of Phytopharmaceuticals From the Amazonian PlantFrontiers in veterinary science · 2020
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Raquel de Oliveira MarreiroSchool of Dentistry, Federal University of Amazonas, Manaus, Amazonas, Brazil.
Maria Fulgência Costa Lima BandeiraSchool of Dentistry, Federal University of Amazonas, Manaus, Amazonas, Brazil.
Tatiane Pereira de SouzaSchool of Pharmacy, Federal University of Amazonas, Manaus, Amazonas, Brazil.
Mailza Costa de AlmeidaSchool of Dentistry, Federal University of Amazonas, Manaus, Amazonas, Brazil.
Katiana BendahamSchool of Dentistry, Federal University of Amazonas, Manaus, Amazonas, Brazil.
Gisely Naura VenâncioSchool of Dentistry, Federal University of Amazonas, Manaus, Amazonas, Brazil.
Isis Costa RodriguesSchool of Pharmacy, Federal University of Amazonas, Manaus, Amazonas, Brazil.
Cristiane Nagai CoelhoSchool of Dentistry, Federal University of Amazonas, Manaus, Amazonas, Brazil.
Patrícia Sâmea Lêdo Lima MilérioSchool of Dentistry, Federal University of Amazonas, Manaus, Amazonas, Brazil.
Glauber Palma de OliveiraSchool of Dentistry, Federal University of Amazonas, Manaus, Amazonas, Brazil.
Nikeila Chacon de Oliveira CondeSchool of Dentistry, Federal University of Amazonas, Manaus, Amazonas, Brazil.
Universidade Federal do Amazonas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biofilm is a dense, whitish, noncalcified aggregate of bacteria, with desquamated epithelial cells and food debris creating conditions for an imbalance of resident oral microflora and favoring the destruction of hard and soft tissues by development of caries and gingivitis. The aim of this study was to obtain and characterize an extract of Libidibia ferrea, ex Caesalpinia ferrea L. and to evaluate its feasibility for formulation as a mouthwash, according to current legislation. For this purpose, pH, sedimentation, density, and stability were evaluated, along with microbiological testing of the extract. The microbiological test was used to verify the presence of Staphylococcus aureus, Pseudomonas aeruginosa, fungi, yeasts, coliforms, and minimum inhibitory concentrations of Streptococcus mutans and Streptococcus oralis strains. Characterization, microbiological evaluation, and minimum inhibitory concentration results were tabulated and described using descriptive statistics. The L. ferrea extract showed stable characteristics, product quality, and antibacterial activity against the microorganisms tested irrespective of experimental time intervals. According to these results, it can be concluded that formulation of a mouthwash containing L. ferrea extract to control biofilm is feasible, but further studies are needed.

Indexed as

biofilmextractquality control

Identifiers

PMID24501546
PMCPMC3912047
OpenAlexW2101388977

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.