ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2014
NG2-glia from pallial progenitors produce the largest clonal clusters of the brain: time frame of clonal generation in cortex and olfactory bulb.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Article
- Diversity of cortical progenitors directs neuronal layer formation and regional glial patterning.Stem cell reports · 2026Article
- Article
- Clonal lineage tracing and transcriptomics of cortical progenitor populations reveal maintenance of differentiation potential.Stem cell reports · 2025Article
- Genetic Tracing of Progenitors from Embryo to Postnatal Brain.Methods in molecular biology (Clifton, N.J.) · 2025Article
- StarTrack: Mapping Cellular Fates with Inheritable Color Codes.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Nerve-Glial antigen 2: unmasking the enigmatic cellular identity in the central nervous system.Frontiers in immunology · 2024Review
- Multicolor strategies for investigating clonal expansion and tissue plasticity.Cellular and molecular life sciences : CMLS · 2022Review
- Development of the mammalian main olfactory bulb.Development (Cambridge, England) · 2022Review
- Lineage Relationships Between Subpallial Progenitors and Glial Cells in the Piriform Cortex.Frontiers in neuroscience · 2022Article
- Article
- In Vivo Clonal Analysis Reveals Development Heterogeneity of Oligodendrocyte Precursor Cells Derived from Distinct Germinal Zones.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
- Life-long oligodendrocyte development and plasticity.Seminars in cell & developmental biology · 2021Article
- Unraveling the adult cell progeny of early postnatal progenitor cells.Scientific reports · 2020Article
- Article
- Lineage Tracing and Cell Potential of Postnatal Single Progenitor Cells In Vivo.Stem cell reports · 2019Article
- A non-hierarchical organization of tumorigenic NG2 cells in glioblastoma promoted by EGFR.Neuro-oncology · 2019Article
- Combining near-infrared fluorescence with Brainbow to visualize expression of specific genes within a multicolor context.Molecular biology of the cell · 2019Article
- Article
- Revisit the Candidacy of Brain Cell Types as the Cell(s) of Origin for Human High-Grade Glioma.Frontiers in molecular neuroscience · 2018Article
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3 authors.
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Abstract
NG2-glia are the most unknown population originating in the CNS. Despite their relative abundance in the brain, fundamental questions about their function, heterogeneity, and origin remain in debate. Particularly, it is still intriguing how these cells escaped from classical in vivo clonal analyses describing other neural types. Using StarTrack labeling in mouse brains, we found that NG2-glia are produced as immense clonal clusters whose number of cells is about one order of magnitude higher than in other neural types. Unexpectedly, this number remained low during embryonic and early postnatal stages, increasing during adulthood. In addition, we also demonstrated a pallial origin of a telencephalic NG2 population, which in the olfactory bulb is derived from local progenitors. Together, our results reveal an original ontogenic process that gives rise to the NG2-glia population and expands the previously established limits of development.
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