ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2014
Tracking progress toward a goal in corticostriatal ensembles.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 70 citations in OpenAlex.
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- Border cells without theta rhythmicity in the medial prefrontal cortex.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Geometric transformation of cognitive maps for generalization across hippocampal-prefrontal circuits.Cell reports · 2023Article
- Review
- Make a Left Turn: Cortico-Striatal Circuitry Mediating the Attentional Control of Complex Movements.Movement disorders : official journal of the Movement Disorder Society · 2021Review
- Neuronal Representation of Locomotion During Motivated Behavior in the Mouse Anterior Cingulate Cortex.Frontiers in systems neuroscience · 2021Article
- Distinct Spiking Patterns of Excitatory and Inhibitory Neurons and LFP Oscillations in Prefrontal Cortex During Sensory Discrimination.Frontiers in physiology · 2021Article
- Prefrontal Neural Ensembles Develop Selective Code for Stimulus Associations within Minutes of Novel Experiences.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Hierarchical Representation of Multistep Tasks in Multiple-Demand and Default Mode Networks.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Corticostriatal stimulation compensates for medial frontal inactivation during interval timing.Scientific reports · 2019Article
- Prefrontal D1 Dopamine-Receptor Neurons and Delta Resonance in Interval Timing.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- A Novel Weight Lifting Task for Investigating Effort and Persistence in Rats.Frontiers in behavioral neuroscience · 2019Article
- Prefrontal cortex and cognitive control: new insights from human electrophysiology.F1000Research · 2019Review
- Human midcingulate cortex encodes distributed representations of task progress.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Coordinated Ramping of Dorsal Striatal Pathways preceding Food Approach and Consumption.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Robust mixture modeling reveals category-free selectivity in reward region neuronal ensembles.Journal of neurophysiology · 2018Article
- Distributed representations of action sequences in anterior cingulate cortex: A recurrent neural network approach.Psychonomic bulletin & review · 2018Article
- Fluid network dynamics in the prefrontal cortex during multiple strategy switching.Nature communications · 2018Article
- Control without Controllers: Toward a Distributed Neuroscience of Executive Control.Journal of cognitive neuroscience · 2017Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
When performing sequences of actions, we constantly keep track of our current position in the sequence relative to the overall goal. The present study searched for neural representations of sequence progression in corticostriatal circuits. Neurons within the anterior cingulate cortex (ACC) and its target region in the dorsal striatum (DS) were recorded from simultaneously as rats performed different sequences of lever presses. We analyzed the responses of the neurons to presses occurring in the "first," "second," or "third" serial position regardless of the particular sequence or physical levers. Principal component analysis revealed that the main source of firing rate variance in the ACC was a smooth ramp-like change as the animal progressed through the sequence toward the reward. No such smooth-ramping activity was observed in DS ensembles as firing tended to be tightly linked to each action. In the ACC, the progression in firing was observed only for correct choices and not errors, whereas in the DS, firing associated with each action in a sequence was similar regardless of whether the action was correct or not. Therefore, different forms of a signal exist within corticostriatal circuits that evolve across a sequence of actions, with DS ensembles tracking every action and ACC ensembles tracking actual progress toward the goal.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.