ArticleJournal of clinical microbiology2014
Distribution of nontuberculous mycobacteria by multigene sequence-based typing and clinical significance of isolated strains.
Article in Journal of clinical microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Co-infection withFrontiers in medicine · 2026Review
- Species distribution of nontuberculous mycobacteria isolated from respiratory specimens at a tertiary care hospital in South Korea, 2017-2022.Microbiology spectrum · 2025Article
- Series 1: The Use ofTropical medicine and infectious disease · 2025Article
- Laboratory-based surveillance of nontuberculous mycobacterial pulmonary disease in Japan.ERJ open research · 2025Article
- Article
- Molecular Identification of Strains within thePolish journal of microbiology · 2023Article
- New RAPMYCOI SensititreDiagnostics (Basel, Switzerland) · 2022Article
- Case report and literature review: double jeopardy -Access microbiology · 2022Article
- Performance of QuantaMatrix Microfluidic Agarose Channel system integrated with mycobacteria growth indicator tube liquid culture.Applied microbiology and biotechnology · 2021Article
- 16S and 23S rRNA Gene Mutation Independent Multidrug Resistance of Non-Tuberculous Mycobacteria Isolated from South Korean Soil.Microorganisms · 2020Article
- Prevalence of nontuberculous mycobacteria in a tertiary hospital in Beijing, China, January 2013 to December 2018.BMC microbiology · 2020Article
- Infection Source and Epidemiology of Nontuberculous Mycobacterial Lung Disease.Tuberculosis and respiratory diseases · 2019Review
- Article
- Implication of species change of Nontuberculous Mycobacteria during or after treatment.BMC pulmonary medicine · 2017Article
- Distribution of non-tuberculosis mycobacteria strains from suspected tuberculosis patients by heat shock protein 65 PCR-RFLP.Saudi journal of biological sciences · 2017Article
- Development of a One-Step Multiplex PCR Assay for Differential Detection of Major Mycobacterium Species.Journal of clinical microbiology · 2017Article
- Taxonomy and systematics of plant probiotic bacteria in the genomic era.AIMS microbiology · 2017Review
- Treatment of Non-Tuberculous Mycobacterial Lung Disease.Current treatment options in infectious diseases · 2016Article
- Diagnosis and Treatment of Nontuberculous Mycobacterial Lung Disease.Journal of Korean medical science · 2016Review
- Diagnosis and Treatment of Nontuberculous Mycobacterial Lung Disease: Clinicians' Perspectives.Tuberculosis and respiratory diseases · 2016Review
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7 authors.
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Abstract
Species identification of nontuberculous mycobacteria (NTM) is challenging due to the increasing number of identified NTM species and the lack of standardized testing strategies. The objectives of this study were to investigate the distribution of NTM species recovered from respiratory specimens by multigene sequence-based typing and to evaluate the clinical significance of identified species. Two hundred thirty-two consecutive clinical NTM isolates were subjected to sequencing of multiple genes, including hsp65, rpoB, and 16S-23S rRNA internal transcribed spacer (ITS) sequence. In addition, clinical data from all patients whose specimens had NTM isolates were analyzed to examine clinical virulence and treatment history. Eighteen strains from 227 isolates from 169 patients were successfully identified at the species level by multigene sequence-based typing. Mycobacterium avium complex and M. abscessus complex made up the majority of isolated NTM (88%; 199/227), followed by M. fortuitum complex (4%; 10/227). The pathogenic potential of NTM differs enormously by species, and M. avium complex and M. abscessus complex revealed especially high levels of virulence compared with findings for other NTM species. The results from our work support M. avium complex and M. abscessus complex being the most common NTM species with highly pathogenic potential isolated from clinical respiratory specimens and could be a good resource for molecular epidemiology of NTM species in South Korea.
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