Evidence map›Paper›PMID 24501025›Full record

ArticleJournal of clinical microbiology2014

Hemolytic uremic syndrome in a 65-Year-old male linked to a very unusual type of stx2e- and eae-harboring O51:H49 shiga toxin-producing Escherichia coli.

Dominique Fasel, Alexander Mellmann, Nicole Cernela, Herbert Hächler, Angelika Fruth, Nina Khanna, Adrian Egli, Christiane Beckmann, Hans H Hirsch, Daniel Goldenberger and 1 more

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 47 citations in OpenAlex.

  1. Predicting clinical outcome ofMicrobial genomics · 2025
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Genomic Characteristics of Stx2e-ProducingPathogens (Basel, Switzerland) · 2021
    Article
  8. Characterization of ClinicalMicroorganisms · 2021
    Article
  9. Article
  10. Article
  11. Review
  12. Validation of a Cell-Based Assay for Detection of Active Shiga Toxins Produced byInternational journal of environmental research and public health · 2020
    Article
  13. Article
  14. Article
  15. Structural Insights intoMicroorganisms · 2019
    Article
  16. Article
  17. Article
  18. Implications of stx loss for clinical diagnostics of Shiga toxin-producing Escherichia coli.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2018
    Article
  19. Article
  20. Characteristics of Shigatoxin-ProducingFrontiers in microbiology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Dominique FaselDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland.
Alexander Mellmann
Nicole Cernela
Herbert Hächler
Angelika Fruth
Nina Khanna
Adrian Egli
Christiane Beckmann
Hans H Hirsch
Daniel Goldenberger
Roger Stephan
University Hospital of Basel · CHUniversity of Zurich · CHRobert Koch Institute · DEUniversity of Basel · CHUniversity of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report on a 65-year-old male patient with a Shiga toxin-producing Escherichia coli O51:H49 gastrointestinal infection and sepsis associated with hemolytic uremic syndrome (HUS) with a fatal outcome. The strains isolated harbored stx2e and eae, a very unusual and new virulence profile for an HUS-associated enterohemorrhagic E. coli.

Indexed as

Adhesins, BacterialAgedEscherichia coli InfectionsEscherichia coli ProteinsFatal OutcomeGastroenteritisHemolytic-Uremic SyndromeHumansMaleSepsisSerogroupShiga-Toxigenic Escherichia coliShiga Toxin 2Virulence FactorsAdhesins, BacterialeaeA protein, E coliEscherichia coli ProteinsShiga Toxin 2Virulence Factors

Identifiers

PMID24501025
PMCPMC3993467
OpenAlexW2167422541

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.