ArticlePlant physiology2014
Scavenging iron: a novel mechanism of plant immunity activation by microbial siderophores.
Article in Plant physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed, 112 citations in OpenAlex.
- Bacterial extracellular vesicles as emerging biostimulants in plant microbe signaling and stress tolerance.World journal of microbiology & biotechnology · 2026Review
- Burkholderia contaminans siderophore-rich supernatants suppress post-harvest anthracnose in avocado fruits.Applied microbiology and biotechnology · 2026Article
- Multiple Plant Growth-Promoting Activities Exhibited by Root-Associated Bacteria Isolated From Bamboo and Corn.International journal of microbiology · 2025Article
- Diversity and potential functional role of phyllosphere-associated actinomycetota isolated from cupuassu (Theobroma grandiflorum) leaves: implications for ecosystem dynamics and plant defense strategies.Molecular genetics and genomics : MGG · 2024Article
- Exploring phyllosphere fungal communities of 29 alpine meadow plant species: composition, structure, function, and implications for plant fungal diseases.Frontiers in microbiology · 2024Article
- The Role of Iron in Phytopathogenic Microbe-Plant Interactions: Insights into Virulence and Host Immune Response.Plants (Basel, Switzerland) · 2023Review
- Suppression of tomato wilt by cell-free supernatants of Acinetobacter baumannii isolates from wild cacao from the Colombian Amazon.World journal of microbiology & biotechnology · 2023Article
- In host evolution of Exophiala dermatitidis in cystic fibrosis lung micro-environment.G3 (Bethesda, Md.) · 2023Article
- A Plant Biostimulant fromPlants (Basel, Switzerland) · 2023Article
- A novel phytopathogenFrontiers in cellular and infection microbiology · 2023Article
- Binding to Iron Quercetin Complexes Increases the Antioxidant Capacity of the Major Birch Pollen Allergen Bet v 1 and Reduces Its Allergenicity.Antioxidants (Basel, Switzerland) · 2022Article
- Oosporein Produced by Root EndophyticPlants (Basel, Switzerland) · 2022Article
- Physiological and Transcriptome Analyses Revealed the Mechanism by Which Deferoxamine Promotes Iron Absorption inInternational journal of molecular sciences · 2022Article
- The receptor kinase SRF3 coordinates iron-level and flagellin dependent defense and growth responses in plants.Nature communications · 2022Article
- Iron redistribution induces oxidative burst and resistance in maize against Curvularia lunata.Planta · 2022Article
- Article
- Efficiency of microbial bio-agents as elicitors in plant defense mechanism under biotic stress: A review.Current research in microbial sciences · 2021Review
- The Knockout of Enterobactin-Related Gene inInternational journal of molecular sciences · 2021Article
- Production of Siderophores by an Apple Root-AssociatedMolecules (Basel, Switzerland) · 2021Article
- Salicylic acid is a key player of Arabidopsis autophagy mutant susceptibility to the necrotrophic bacterium Dickeya dadantii.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Siderophores are specific ferric iron chelators synthesized by virtually all microorganisms in response to iron deficiency. We have previously shown that they promote infection by the phytopathogenic enterobacteria Dickeya dadantii and Erwinia amylovora. Siderophores also have the ability to activate plant immunity. We have used complete Arabidopsis transcriptome microarrays to investigate the global transcriptional modifications in roots and leaves of Arabidopsis (Arabidopsis thaliana) plants after leaf treatment with the siderophore deferrioxamine (DFO). Physiological relevance of these transcriptional modifications was validated experimentally. Immunity and heavy-metal homeostasis were the major processes affected by DFO. These two physiological responses could be activated by a synthetic iron chelator ethylenediamine-di(o-hydroxyphenylacetic) acid, indicating that siderophores eliciting activities rely on their strong iron-chelating capacity. DFO was able to protect Arabidopsis against the pathogenic bacterium Pseudomonas syringae pv tomato DC3000. Siderophore treatment caused local modifications of iron distribution in leaf cells visible by ferrocyanide and diaminobenzidine-H₂O₂ staining. Metal quantifications showed that DFO causes a transient iron and zinc uptake at the root level, which is presumably mediated by the metal transporter iron regulated transporter1 (IRT1). Defense gene expression and callose deposition in response to DFO were compromised in an irt1 mutant. Consistently, plant susceptibility to D. dadantii was increased in the irt1 mutant. Our work shows that iron scavenging is a unique mechanism of immunity activation in plants. It highlights the strong relationship between heavy-metal homeostasis and immunity.
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