Evidence map›Paper›PMID 24500705›Full record

ReviewPediatric nephrology (Berlin, Germany)2014

Vesicoureteric reflux and reflux nephropathy: from mouse models to childhood disease.

Marie-Lyne Fillion, Christine L Watt, Indra R Gupta

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03959163 (The Validity of the Quick Renal MRI in Pediatric Kidney Disease), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03959163 narecruitingnot on this mapstarted 2019, after this paper: background citation

The Validity of the Quick Renal MRI in Pediatric Kidney Disease

TypeinterventionalSponsorUniversity of Wisconsin, MadisonRan2019 to 2025Enrolled100ConditionsPyelonephritis, Pyelonephritis Acute, Renal SclerosisArmsQuick MRI
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Primary vesicoureteral reflux.Nature reviews. Disease primers · 2024
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. The First Thousand Days: Kidney Health and Beyond.Healthcare (Basel, Switzerland) · 2021
    Review
  9. Article
  10. Article
  11. Article
  12. Acidosis induces antimicrobial peptide expression and resistance to uropathogenicAmerican journal of physiology. Renal physiology · 2020
    Article
  13. Review
  14. Article
  15. Vesicoureteral reflux and the extracellular matrix connection.Pediatric nephrology (Berlin, Germany) · 2017
    Review
  16. Article
  17. Article
  18. Urinary excretion of EGF and MCP-1 in children with vesicoureteral reflux.International braz j urol : official journal of the Brazilian Society of Urology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Marie-Lyne FillionDepartment of Human Genetics, McGill University, Montreal, Quebec, Canada.
Christine L Watt
Indra R Gupta
McGill University · CAMcGill University Health Centre · CA

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

Vesicoureteric reflux (VUR) is a common congenital urinary tract defect that predisposes children to recurrent kidney infections. Kidney infections can result in renal scarring or reflux nephropathy defined by the presence of chronic tubulo-interstitial inflammation and fibrosis that is a frequent cause of end-stage renal failure. The discovery of mouse models with VUR and with reflux nephropathy has provided new opportunities to understand the pathogenesis of these conditions and may provide insight on the genes and the associated phenotypes that need to be examined in human studies.

Indexed as

AnimalsDisease Models, AnimalHumansKidney DiseasesMiceUrogenital SystemVesico-Ureteral Reflux

Identifiers

PMID24500705
OpenAlexW2005760713

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.