ReviewCurrent opinion in anaesthesiology2014
Merits of exercise therapy before and after major surgery.
Review in Current opinion in anaesthesiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04017858 (PARQVE Prior to Total Knee Replacement), which is not on this map. Cited by 63 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
PARQVE Prior to Total Knee Replacement
Who cites it
63 citing papers in PubMed, 8 syntheses or guidelines pooled it, 216 citations in OpenAlex.
- Pooled it
- Predictive factors for postoperative outcomes after reverse shoulder arthroplasty: a systematic review.BMC musculoskeletal disorders · 2024Pooled it
- Prehabilitation for Patients Undergoing Orthopedic Surgery: A Systematic Review and Meta-analysis.JAMA network open · 2023Pooled it
- Prophylactic alpha blockers fail to prevent postoperative urinary retention following orthopaedic procedures: evidence from a meta-analysis and trial sequential analysis of comparative studies.Frontiers in pharmacology · 2023Pooled it
- Physical Effects, Safety and Feasibility of Prehabilitation in Patients Awaiting Orthotopic Liver Transplantation, a Systematic Review.Transplant international : official journal of the European Society for Organ Transplantation · 2022Pooled it
- Prehabilitation exercise therapy before elective abdominal aortic aneurysm repair.The Cochrane database of systematic reviews · 2021Pooled it
- Prehabilitation Programs Improve Exercise Capacity Before and After Surgery in Gastrointestinal Cancer Surgery Patients: A Meta-Analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020Pooled it
- Combined Lower Limb Revascularisation and Supervised Exercise Training for Patients with Peripheral Arterial Disease: A Systematic Review of Randomised Controlled Trials.Sports medicine (Auckland, N.Z.) · 2017Pooled it
- The effect of prehabilitation for older patients awaiting total hip replacement. A randomized controlled trial with long-term follow up.BMC musculoskeletal disorders · 2025Trial
- The Effect of a Smartphone App with an Accelerometer on the Physical Activity Behavior of Hospitalized Patients: A Randomized Controlled Trial.Sensors (Basel, Switzerland) · 2023Trial
- Preoperative Rehabilitation Is Feasible in the Weeks Prior to Surgery and Significantly Improves Functional Performance.The Journal of frailty & aging · 2023Trial
- Prehabilitation in patients undergoing colorectal surgery fails to confer reduction in overall morbidity: results of a single-center, blinded, randomized controlled trial.Langenbeck's archives of surgery · 2022Trial
- Pre-operative physiotherapy for elderly patients undergoing abdominal surgery.The South African journal of physiotherapy · 2022Trial
- Association of a prehabilitation program with anxiety and depression before colorectal surgery: a post hoc analysis of the pERACS randomized controlled trial.Langenbeck's archives of surgery · 2021Trial
- 'Prehabilitation Should Adapt to the Person, not the Other Way Around': A Qualitative Study Exploring Stakeholder Perceptions of Prehabilitation for Total Hip and Knee Arthroplasty.Musculoskeletal care · 2026Article
- Experiences of post-surgery exercise among middle-aged adults with early lung cancer.Open medicine (Warsaw, Poland) · 2026Article
- Development of a Cocreated Perioperative Joint Replacement Digital Care Pathway to Improve Surgical Outcomes Following Joint Replacement: Protocol for a Mixed Methods Study.JMIR research protocols · 2025Article
- Changing the narrative for exercise-based prehabilitation: Evidence-informed and shared decision making when discussing the need for a total knee arthroplasty with patients.Osteoarthritis and cartilage open · 2025Review
- Association of Preoperative Functional Status With Short-Term Major Adverse Outcomes After Cardiac Surgery.Cureus · 2025Article
- Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewAdvances in medical care have led to an increasing elderly population. Elderly individuals should be able to participate in society as long as possible. However, with an increasing age their adaptive capacity gradually decreases, specially before and after major life events (like hospitalization and surgery) making them vulnerable to reduced functioning and societal participation. Therapeutic exercise before and after surgery might augment the postoperative outcomes by improving functional status and reducing the complication and mortality rate. RECENT
findingsThere is high quality evidence that preoperative exercise in patients scheduled for cardiovascular surgery is well tolerated and effective. Moreover, there is circumstantial evidence suggesting preoperative exercise for thoracic, abdominal and major joint replacement surgery is effective, provided that this is offered to the high-risk patients. Postoperative exercise should be initiated as soon as possible after surgery according to fast-track or enhanced recovery after surgery principles. SUMMARY: The perioperative exercise training protocol known under the name 'Better in, Better out' could be implemented in clinical care for the vulnerable group of patients scheduled for major elective surgery who are at risk for prolonged hospitalization, complications and/or death. Future research should aim to include this at-risk group, evaluate perioperative high-intensity exercise interventions and conduct adequately powered trials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.