ArticleProceedings. Biological sciences2014
Insulin signalling underlies both plasticity and divergence of a reproductive trait in Drosophila.
Article in Proceedings. Biological sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Evolution of Size-Fecundity Relationship in Medaka Fish From Different Latitudes.Molecular ecology · 2024Article
- Larval and/or Adult Exposure to Intraguild PredatorInsects · 2023Article
- Niche formation and function in developing tissue: studies from the Drosophila ovary.Cell communication and signaling : CCS · 2023Review
- Evaluation of Body Size Indicators for Morphological Analyses in Two Sister Species of Genus Dorcus (Coleoptera, Lucanidae).Journal of insect science (Online) · 2022Article
- Article
- Distinct gene expression dynamics in germ line and somatic tissue during ovariole morphogenesis in Drosophila melanogaster.G3 (Bethesda, Md.) · 2022Article
- Target of Rapamycin Drives Unequal Responses to Essential Amino Acid Depletion for Egg Laying inFrontiers in cell and developmental biology · 2022Article
- Genetic manipulation of insulin/insulin-like growth factor signaling pathway activity has sex-biased effects on Drosophila body size.G3 (Bethesda, Md.) · 2021Article
- Sex and tissue-specific evolution of developmental plasticity inEcology and evolution · 2021Article
- Article
- Transcriptional Regulation ofGenes · 2019Review
- Reproductive Capacity Evolves in Response to Ecology through Common Changes in Cell Number in Hawaiian Drosophila.Current biology : CB · 2019Article
- Ancestral and offspring nutrition interact to affect life-history traits in Drosophila melanogaster.Proceedings. Biological sciences · 2019Article
- Perturbation of IIS/TOR signaling alters the landscape of sex-differential gene expression in Drosophila.BMC genomics · 2018Article
- Lmx1a is required for the development of the ovarian stem cell niche inDevelopment (Cambridge, England) · 2018Article
- Review
- The Genetic Architecture of Ovariole Number inG3 (Bethesda, Md.) · 2017Article
- Article
- Stage-Specific Plasticity in Ovary Size Is Regulated by Insulin/Insulin-Like Growth Factor and Ecdysone Signaling in Drosophila.Genetics · 2016Article
- The Hippo pathway regulates homeostatic growth of stem cell niche precursors in the Drosophila ovary.PLoS genetics · 2015Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Phenotypic plasticity is the ability of a single genotype to yield distinct phenotypes in different environments. The molecular mechanisms linking phenotypic plasticity to the evolution of heritable diversification, however, are largely unknown. Here, we show that insulin/insulin-like growth factor signalling (IIS) underlies both phenotypic plasticity and evolutionary diversification of ovariole number, a quantitative reproductive trait, in Drosophila. IIS activity levels and sensitivity have diverged between species, leading to both species-specific ovariole number and species-specific nutritional plasticity in ovariole number. Plastic range of ovariole number correlates with ecological niche, suggesting that the degree of nutritional plasticity may be an adaptive trait. This demonstrates that a plastic response conserved across animals can underlie the evolution of morphological diversity, underscoring the potential pervasiveness of plasticity as an evolutionary mechanism.
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