ArticleParasites & vectors2013
Patterns of phenoloxidase activity in insecticide resistant and susceptible mosquitoes differ between laboratory-selected and wild-caught individuals.
Article in Parasites & vectors, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 37 citations in OpenAlex.
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- Global, asynchronous partial sweeps at multiple insecticide resistance genes in Aedes mosquitoes.Nature communications · 2024Article
- Phenotypic resistance not associated with knockdown mutations (kdr) in Anopheles albimanus exposed to deltamethrin in southern coastal Ecuador.Malaria journal · 2024Article
- Generation of specific immune memory by bacterial exposure in the major malaria vectorCurrent research in insect science · 2024Article
- Higher temperature accelerates the aging-dependent weakening of the melanization immune response in mosquitoes.PLoS pathogens · 2024Article
- Cuticular profiling of insecticide resistant Aedes aegypti.Scientific reports · 2023Article
- Impact of insecticide resistance on malaria vector competence: a literature review.Malaria journal · 2023Review
- Beauveria bassiana interacts with gut and hemocytes to manipulate Aedes aegypti immunity.Parasites & vectors · 2023Article
- Cuticular profiling of insecticide resistantbioRxiv : the preprint server for biology · 2023Article
- Review
- Persistent pesticides: effects of endosulfan at the molecular level on the aquatic invertebrate Chironomus riparius.Environmental science and pollution research international · 2021Article
- Glyphosate inhibits melanization and increases susceptibility to infection in insects.PLoS biology · 2021Article
- Insecticide resistance, fitness and susceptibility to Zika infection of an interbred Aedes aegypti population from Rio de Janeiro, Brazil.Parasites & vectors · 2020Article
- Larval exposure to a pyrethroid insecticide and competition for food modulate the melanisation and antibacterial responses of adult Anopheles gambiae.Scientific reports · 2020Article
- Anopheles gambiae larvae mount stronger immune responses against bacterial infection than adults: evidence of adaptive decoupling in mosquitoes.Parasites & vectors · 2017Article
- Mosquito age and avian malaria infection.Malaria journal · 2015Article
- Avian malaria: a new lease of life for an old experimental model to study the evolutionary ecology of Plasmodium.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015Article
- A neuron-specific antiviral mechanism prevents lethal flaviviral infection of mosquitoes.PLoS pathogens · 2015Article
- Larvicidal effect of disinfectant soap on Anopheles gambiae s.s (Diptera: Culicidae) in laboratory and semifield environs.Parasites & vectors · 2014Article
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundInsecticide resistance has the potential to alter vector immune competence and consequently affect the transmission of diseases.
methodsUsing both laboratory isogenic strains and field-caught Culex pipiens mosquitoes, we investigated the effects of insecticide resistance on an important component of the mosquito immune system: the phenoloxidase (PO) activity. As infection risk varies dramatically with the age and sex of mosquitoes, allocation to PO immunity was quantified across different stages of the mosquito life cycle.
resultsOur results were consistent in showing that larvae have a higher PO activity than adults, females have a higher PO activity than males, and PO activity declines with adult age. We obtained, however, a marked discrepancy between laboratory and field-collected mosquitoes on the effect of insecticide resistance on PO activity. In the laboratory selected strains we found evidence of strong interactions between insecticide resistance and the age and sex of mosquitoes. In particular, 7 and 14 day old esterase-resistant adult females and acetylcholine-esterase resistant males had significantly higher PO activities than their susceptible counterparts. No such effects were, however, apparent in field-caught mosquitoes.
conclusionsCombined, the field and laboratory-based approaches employed in this study provide a powerful test of the effect of insecticide resistance on PO-mediated immunity. The use of laboratory-selected insecticide-resistant strains is still the most widely used method to investigate the pleiotropic effects of insecticide resistance. Our results suggest that the outcome of these laboratory-selected mosquitoes must be interpreted with caution and, whenever possible, compared with mosquitoes captured from the field.
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