ArticlePloS one2014
Wolbachia divergence and the evolution of cytoplasmic incompatibility in Culex pipiens.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 69 citations in OpenAlex.
- Genomic islands in Wolbachia prophages drive amplification and diversification of cytoplasmic incompatibility genes in Culex pipiens.Genetics · 2026Article
- Extensive mobilome dynamics in a widespread endosymbiont: long read metagenomics reveal dimeric plasmids and highly fragmented prophages in Wolbachia from Culex pipiens.Research square · 2026Article
- Recombination, Truncation and Horizontal Transfer Shape the Diversity of Wolbachia-induced Cytoplasmic Incompatibility Patterns.Molecular biology and evolution · 2025Article
- EuropeanInsects · 2024Article
- Genomic Underpinnings of Cytoplasmic Incompatibility: CIF Gene-Neighborhood Diversification Through Extensive Lateral Transfers and Recombination in Wolbachia.Genome biology and evolution · 2024Article
- Review
- Intra-lineage microevolution of Wolbachia leads to the emergence of new cytoplasmic incompatibility patterns.PLoS biology · 2024Article
- Article
- Genetic diversity of endosymbiotic bacteriaFrontiers in microbiology · 2024Article
- Investigation of Cytoplasmic Incompatibility Patterns in Culex pipiens: From Field Samples to Laboratory Isofemale Lines.Methods in molecular biology (Clifton, N.J.) · 2024Article
- First Detection and Genetic Identification ofMicroorganisms · 2023Article
- Screening of natural Wolbachia infection in mosquitoes (Diptera: Culicidae) from the Cape Verde islands.Parasites & vectors · 2023Article
- No association between habitat, autogeny and genetics in Moroccan Culex pipiens populations.Parasites & vectors · 2022Article
- Management of avian malaria in populations of high conservation concern.Parasites & vectors · 2022Review
- Article
- Experimental evidence ofCurrent zoology · 2021Article
- Molecular Detection and Genetic Identification of Wolbachia Endosymbiont in Wild-Caught Culex quinquefasciatus (Diptera: Culicidae) Mosquitoes from Sumatera Utara, Indonesia.Microbial ecology · 2021Article
- Article
- Life and Death of Selfish Genes: Comparative Genomics Reveals the Dynamic Evolution of Cytoplasmic Incompatibility.Molecular biology and evolution · 2021Article
- An elusive endosymbiont: DoesEcology and evolution · 2020Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many insect species harbor Wolbachia bacteria that induce cytoplasmic incompatibility (CI), i.e. embryonic lethality in crosses between infected males and uninfected females, or between males and females carrying incompatible Wolbachia strains. The molecular mechanism of CI remains unknown, but the available data are best interpreted under a modification-rescue model, where a mod function disables the reproductive success of infected males' sperm, unless the eggs are infected and express a compatible resc function. Here we examine the evolution of CI in the mosquito Culex pipiens, harbouring a large number of closely related Wolbachia strains structured in five distinct phylogenetic groups. Specifically, we used a worldwide sample of mosquito lines to assess the hypothesis that genetic divergence should correlate with the divergence of CI properties on a low evolutionary scale. We observed a significant association of Wolbachia genetic divergence with CI patterns. Most Wolbachia strains from the same group were compatible whereas those from different groups were often incompatible. Consistently, we found a strong association between Wolbachia groups and their mod-resc properties. Finally, lines from the same geographical area were rarely incompatible, confirming the conjecture that the spatial distribution of Wolbachia compatibility types should be constrained by selection. This study indicates a clear correlation between Wolbachia genotypes and CI properties, paving the way toward the identification of the molecular basis of CI through comparative genomics.
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