Evidence map›Paper›PMID 24497790›Full record

ArticleKorean journal of radiology

Accuracy of high-resolution MRI with lumen distention in rectal cancer staging and circumferential margin involvement prediction.

Elsa Iannicelli, Sara Di Renzo, Mario Ferri, Emanuela Pilozzi, Marco Di Girolamo, Alessandra Sapori, Vincenzo Ziparo, Vincenzo David

Open access · hybridAbstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Korean journal of radiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 55 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Elsa IannicelliRadiology Institute, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant'Andrea Hospital, Rome 00189, Italy. ; Department of Surgical and Medical Sciences and Translational Medicine, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant'Andrea Hospital, Rome 00189, Italy.
Sara Di RenzoRadiology Institute, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant'Andrea Hospital, Rome 00189, Italy. ; Department of Surgical and Medical Sciences and Translational Medicine, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant'Andrea Hospital, Rome 00189, Italy.
Mario FerriDepartment of Surgical and Medical Sciences and Translational Medicine, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant'Andrea Hospital, Rome 00189, Italy.
Emanuela PilozziDepartment of Clinical and Molecular Sciences, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant'Andrea Hospital, Rome 00189, Italy.
Marco Di GirolamoRadiology Institute, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant'Andrea Hospital, Rome 00189, Italy. ; Department of Surgical and Medical Sciences and Translational Medicine, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant'Andrea Hospital, Rome 00189, Italy.
Alessandra SaporiRadiology Institute, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant'Andrea Hospital, Rome 00189, Italy. ; Department of Surgical and Medical Sciences and Translational Medicine, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant'Andrea Hospital, Rome 00189, Italy.
Vincenzo ZiparoDepartment of Surgical and Medical Sciences and Translational Medicine, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant'Andrea Hospital, Rome 00189, Italy.
Vincenzo DavidRadiology Institute, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant'Andrea Hospital, Rome 00189, Italy. ; Department of Surgical and Medical Sciences and Translational Medicine, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant'Andrea Hospital, Rome 00189, Italy.
Azienda Ospedaliera Sant'Andrea · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the accuracy of magnetic resonance imaging (MRI) with lumen distention for rectal cancer staging and circumferential resection margin (CRM) involvement prediction. MATERIALS AND

methodsSeventy-three patients with primary rectal cancer underwent high-resolution MRI with a phased-array coil performed using 60-80 mL room air rectal distention, 1-3 weeks before surgery. MRI results were compared to postoperative histopathological findings. The overall MRI T staging accuracy was calculated. CRM involvement prediction and the N staging, the accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were assessed for each T stage. The agreement between MRI and histological results was assessed using weighted-kappa statistics.

resultsThe overall MRI accuracy for T staging was 93.6% (k = 0.85). The accuracy, sensitivity, specificity, PPV and NPV for each T stage were as follows: 91.8%, 86.2%, 95.5%, 92.6% and 91.3% for the group ≤ T2; 90.4%, 94.6%, 86.1%, 87.5% and 94% for T3; 98,6%, 85.7%, 100%, 100% and 98.5% for T4, respectively. The predictive CRM accuracy was 94.5% (k = 0.86); the sensitivity, specificity, PPV and NPV were 89.5%, 96.3%, 89.5%, and 96.3% respectively. The N staging accuracy was 68.49% (k = 0.4).

conclusionMRI performed with rectal lumen distention has proved to be an effective technique both for rectal cancer staging and involved CRM predicting.

Indexed as

AirAdultAgedDilatationFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedNeoplasm StagingProspective StudiesRectal NeoplasmsRectumSensitivity and SpecificityRectum MRRectum NEOPLASMRectum staging

Identifiers

PMID24497790
PMCPMC3909859
OpenAlexW2131558262

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.