Evidence map›Paper›PMID 24497673›Full record

ReviewIndian journal of urology : IJU : journal of the Urological Society of India2014

Risks of testosterone replacement therapy in men.

E Charles Osterberg, Aaron M Bernie, Ranjith Ramasamy

Registry-linked trialOpen access · diamondAbstract readReview
In one paragraph

Review in Indian journal of urology : IJU : journal of the Urological Society of India, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07143474 (A Randomized Double-blind Placebo Controlled Clinical Study to Evaluate the Impacts of RhizomK as Compared to Placebo on Testosterone Levels, the Anabolic Response to Exercise and Overall Quality of Life in Physically Active Healthy Males), which is not on this map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07143474 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

A Randomized Double-blind Placebo Controlled Clinical Study to Evaluate the Impacts of RhizomK as Compared to Placebo on Testosterone Levels, the Anabolic Response to Exercise and Overall Quality of Life in Physically Active Healthy Males

TypeinterventionalSponsorAll India Institute of Medical Sciences, BhubaneswarRan2025 to 2027Enrolled60ConditionsAdult Healthy VolunteersArmsRhizomK, Plcebo
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 86 citations in OpenAlex.

  1. Trial
  2. Efficacy and Safety of TESTOPEAKAmerican journal of men's health
    Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Effect of Elderberry (Nutrients · 2024
    Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Effect ofNutrients · 2022
    Article
  19. The Roles of Androgens in Humans: Biology, Metabolic Regulation and Health.International journal of molecular sciences · 2022
    Review
  20. Nuclear hormone receptors in demyelinating diseases.Journal of neuroendocrinology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

E Charles OsterbergDepartment of Urology, New York Presbyterian Hospital, Weill Cornell Medical College, Starr 900, New York, NY, USA.
Aaron M BernieDepartment of Urology, New York Presbyterian Hospital, Weill Cornell Medical College, Starr 900, New York, NY, USA.
Ranjith RamasamyDepartment of Urology, New York Presbyterian Hospital, Weill Cornell Medical College, Starr 900, New York, NY, USA.
Cornell University · USNewYork–Presbyterian Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Testosterone replacement therapy (TRT) is a widely used treatment for men with symptomatic hypogonadism. The benefits seen with TRT, such as increased libido and energy level, beneficial effects on bone density, strength and muscle as well as cardioprotective effects, have been well-documented. TRT is contraindicated in men with untreated prostate and breast cancer. Men on TRT should be monitored for side-effects such as polycythemia, peripheral edema, cardiac and hepatic dysfunction.

Indexed as

Hypogonadismside-effectstestosterone replacement therapy

Identifiers

PMID24497673
PMCPMC3897047
OpenAlexW2055947384

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.