ArticleSleep2014
Regional reductions in sleep electroencephalography power in obstructive sleep apnea: a high-density EEG study.
Article in Sleep, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 91 citations in OpenAlex.
- Sleep Apnea Detection Using EEG: A Systematic Review of Datasets, Methods, Challenges, and Future Directions.Annals of biomedical engineering · 2025Pooled it
- Acute Effects of Oral Cannabinoids on Sleep and High-Density EEG in Insomnia: A Pilot Randomised Controlled Trial.Journal of sleep research · 2026Trial
- Paroxysmal slow wave events are associated with cognitive impairment in patients with obstructive sleep apnea.Alzheimer's research & therapy · 2022Trial
- Sleep EEG microstructure is associated with neurobehavioural impairment after extended wakefulness in obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2021Trial
- High Resolution Topography of Age-Related Changes in Non-Rapid Eye Movement Sleep Electroencephalography.PloS one · 2016Trial
- Sleep homeostasis impairment across obstructive sleep apnea severity: findings from a population-based cohort study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026Article
- Article
- Abnormal local markers of sleep homeostasis in patients with focal epilepsy.Brain communications · 2026Article
- Article
- Sleep as a window into brain health: clinical implications of sleeping brain wave-structure associations.Sleep · 2025Article
- Tripolar concentric ring electrodes for capturing localised electroencephalography signals during sleep.Journal of sleep research · 2024Article
- From macro to micro: slow-wave sleep and its pivotal health implications.Frontiers in sleep · 2024Review
- Abnormal interaction between cortical regions of obstructive sleep apnea hypopnea syndrome children.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Article
- Sleep slow waves' negative-to-positive-phase transition: a marker of cognitive and apneic status in aging.Sleep · 2023Article
- EEG Power Spectral Density in NREM Sleep is Associated with the Degree of Hypoxia in Patients with Obstructive Sleep Apnea.Nature and science of sleep · 2023Article
- Article
- The association between sleep microarchitecture and cognitive function in middle-aged and older men: a community-based cohort study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Nine-day continuous recording of EEG and 2-hour of high-density EEG under chronic sleep restriction in mice.Scientific data · 2022Article
- Gulf War veterans exhibit broadband sleep EEG power reductions in regions overlying the frontal lobe.Life sciences · 2021Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
STUDY
objectivesObstructive sleep apnea (OSA) is associated with significant alterations in neuronal integrity resulting from either hypoxemia and/or sleep loss. A large body of imaging research supports reductions in gray matter volume, alterations in white matter integrity and resting state activity, and functional abnormalities in response to cognitive challenge in various brain regions in patients with OSA. In this study, we used high-density electroencephalography (hdEEG), a functional imaging tool that could potentially be used during routine clinical care, to examine the regional distribution of neural activity in a non-clinical sample of untreated men and women with moderate/severe OSA.
designSleep was recorded with 256-channel EEG in relatively healthy subjects with apnea-hypopnea index (AHI) > 10, as well as age-, sex-, and body mass index-matched controls selected from a research population initially recruited for a study on sleep and meditation.
settingSleep laboratory. PATIENTS OR
participantsNine subjects with AHI > 10 and nine matched controls.
interventionsN/A. MEASUREMENTS AND
resultsTopographic analysis of hdEEG data revealed a broadband reduction in EEG power in a circumscribed region overlying the parietal cortex in OSA subjects. This parietal reduction in neural activity was present, to some extent, across all frequency bands in all stages and episodes of nonrapid eye movement sleep.
conclusionThis investigation suggests that regional deficits in electroencephalography (EEG) power generation may be a useful clinical marker for neural disruption in obstructive sleep apnea, and that high-density EEG may have the sensitivity to detect pathological cortical changes early in the disease process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.