Evidence map›Paper›PMID 24497661›Full record

Trial reportSleep2014

Cognitive behavioral therapy for insomnia in posttraumatic stress disorder: a randomized controlled trial.

Lisa S Talbot, Shira Maguen, Thomas J Metzler, Martha Schmitz, Shannon E McCaslin, Anne Richards, Michael L Perlis, Donn A Posner, Brandon Weiss, Leslie Ruoff and 2 more

2 registry-linked trialsOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Sleep, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 130 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
130citing papers in PubMed, 10 pooled it
24.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00881647 nacompletednot on this map

Cognitive Behavioral Treatment of Insomnia in Posttraumatic Stress Disorder

TypeinterventionalSponsorUniversity of California, San FranciscoRan2008 to 2013Enrolled45ConditionsPost-Traumatic Stress DisorderArmsCognitive Behavioral Treatment for Insomnia (CBT-I)
NCT04956341 naactive not recruitingnot on this mapstarted 2022, after this paper: background citation

Auricular Acupuncture for Sleep Disturbances: A Randomized Control Trial

TypeinterventionalSponsorPaul CrawfordRan2022 to 2026Enrolled180ConditionsSleep DisturbanceArmsAuricular acupuncture, Standard treatment
3 · Its place in the literature

Who cites it

130 citing papers in PubMed, 10 syntheses or guidelines pooled it, 284 citations in OpenAlex.

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  9. Position Paper for the Treatment of Nightmare Disorder in Adults: An American Academy of Sleep Medicine Position Paper.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2018
    Guideline
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  11. Results of a pilot randomized controlled trial of CBT-I for veterans with serious mental illness and insomnia.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Trial
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  16. Cognitive behavioral therapy for insomnia treatment attrition in patients with weekly nightmares.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Trial
  17. Transdiagnostic cognitive behavioral therapy for nightmares and parasomnias.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Trial
  18. Brief behavioral treatment for insomnia decreases trauma-related nightmare frequency in veterans.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Trial
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  20. Trial

70 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Lisa S TalbotSan Francisco VA Medical Center, San Francisco, CA ; Department of Psychiatry, University of California, San Francisco, CA.
Shira MaguenSan Francisco VA Medical Center, San Francisco, CA ; Department of Psychiatry, University of California, San Francisco, CA.
Thomas J MetzlerSan Francisco VA Medical Center, San Francisco, CA.
Martha SchmitzSan Francisco VA Medical Center, San Francisco, CA ; Department of Psychiatry, University of California, San Francisco, CA.
Shannon E McCaslinSan Francisco VA Medical Center, San Francisco, CA ; Department of Psychiatry, University of California, San Francisco, CA ; National Center for PTSD, VA Palo Alto Health Care System, Palo Alto, CA.
Anne RichardsSan Francisco VA Medical Center, San Francisco, CA ; Department of Psychiatry, University of California, San Francisco, CA.
Michael L PerlisDepartment of Psychiatry, University of Pennsylvania, Philadelphia, PA.
Donn A PosnerDepartment of Psychiatry and Human Behavior, Brown University, Providence, RI.
Brandon WeissSan Francisco VA Medical Center, San Francisco, CA.
Leslie RuoffSan Francisco VA Medical Center, San Francisco, CA.
Jonathan VarbelSan Francisco VA Medical Center, San Francisco, CA.
Thomas C NeylanSan Francisco VA Medical Center, San Francisco, CA ; Department of Psychiatry, University of California, San Francisco, CA.
San Francisco VA Medical Center · USUniversity of California, San Francisco · USBrown University · USUniversity of Pennsylvania · USVA Palo Alto Health Care System · US

Funding

Neuroendocrine Regulation of Sleep in PTSDR01MH073978 · NIMH · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI NEYLAN, THOMAS C · 2005 to 2008
$1.8M
Cognitive Behavioral Treatment of Insomnia in Posttraumatic Stress DisorderR34MH077667 · NIMH · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI NEYLAN, THOMAS C · 2008 to 2010
$638k
NIMH NIH HHS 5R01MH073978-04NIMH NIH HHS 5R34MH077667-03NIMH NIH HHS R34 MH077667
6 · The paper itself

Abstract

STUDY

objectivesExamine whether cognitive behavioral therapy for insomnia (CBT-I) improves sleep in posttraumatic stress disorder (PTSD) as well as nightmares, nonsleep PTSD symptoms, depression symptoms, and psychosocial functioning.

designRANDOMIZED CONTROLLED TRIAL WITH TWO ARMS: CBT-I and monitor-only waitlist control.

settingDepartment of Veterans Affairs (VA) Medical Center.

participantsForty-five adults (31 females: [mean age 37 y (22-59 y)] with PTSD meeting research diagnostic criteria for insomnia, randomly assigned to CBT-I (n = 29; 22 females) or monitor-only waitlist control (n = 16; nine females).

interventionsEight-session weekly individual CBT-I delivered by a licensed clinical psychologist or a board-certified psychiatrist. MEASUREMENTS AND

resultsMeasures included continuous monitoring of sleep with diary and actigraphy; prepolysomnography and postpolysomnography and Clinician-Administered PTSD Scale (CAPS); and pre, mid, and post self-report questionnaires, with follow-up of CBT-I participants 6 mo later. CBT-I was superior to the waitlist control condition in all sleep diary outcomes and in polysomnography-measured total sleep time. Compared to waitlist participants, CBT-I participants reported improved subjective sleep (41% full remission versus 0%), disruptive nocturnal behaviors (based on the Pittsburgh Sleep Quality Index-Addendum), and overall work and interpersonal functioning. These effects were maintained at 6-mo follow-up. Both CBT-I and waitlist control participants reported reductions in PTSD symptoms and CAPS-measured nightmares.

conclusionsCognitive behavioral therapy for insomnia (CBT-I) improved sleep in individuals with posttraumatic stress disorder, with durable gains at 6 mo. Overall psychosocial functioning improved following CBT-I. The initial evidence regarding CBT-I and nightmares is promising but further research is needed. Results suggest that a comprehensive approach to treatment of posttraumatic stress disorder should include behavioral sleep medicine. CLINICAL TRIAL INFORMATION: TRIAL NAME: Cognitive Behavioral Treatment Of Insomnia In Posttraumatic Stress Disorder. URL: http://clinicaltrials.gov/ct2/show/NCT00881647. REGISTRATION NUMBER: NCT00881647.

Indexed as

Cognitive Behavioral TherapySocial BehaviorActigraphyAdultDepressionDreamsFemaleHumansMaleMiddle AgedPatient CompliancePatient DropoutsPolysomnographySan FranciscoSleep Initiation and Maintenance DisordersSleep Stagescognitive behavioral therapyInsomniaposttraumatic stress disorder

Identifiers

PMID24497661
PMCPMC3900619
OpenAlexW1996887654

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.