Collaborating constitutive and somatic genetic events in myeloid malignancies: ASXL1 mutations in patients with germline GATA2 mutations.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

20 citing papers in PubMed.

1. How I treat AML incorporating the updated classifications and guidelines.Blood · 2023
   Article
2. Infection and myelodysplasia: A case report of GATA2 deficiency in a South African patient.Clinical case reports · 2023
   Article
3. Molecular Pathogenesis in Myeloid Neoplasms with Germline Predisposition.Life (Basel, Switzerland) · 2021
   Review
4. Advances in germline predisposition to acute leukaemias and myeloid neoplasms.Nature reviews. Cancer · 2021
   Review
5. Role of GATA2 in Human NK Cell Development.Critical reviews in immunology · 2021
   Review
6. The Genomics of Myelodysplastic Syndromes: Origins of Disease Evolution, Biological Pathways, and Prognostic Implications.Cells · 2020
   Review
7. The role of ASXL1 in hematopoiesis and myeloid malignancies.Cellular and molecular life sciences : CMLS · 2019
   Review
8. [Clinical and molecular characteristics of GATA2 related pediatric primary myelodysplastic syndrome].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2019
   Article
9. Transcription factor mutations as a cause of familial myeloid neoplasms.The Journal of clinical investigation · 2019
   Review
10. Significance of Clonal Mutations in Bone Marrow Failure and Inherited Myelodysplastic Syndrome/Acute Myeloid Leukemia Predisposition Syndromes.Hematology/oncology clinics of North America · 2018
    Review
11. Germline GATA2 Mutation and Bone Marrow Failure.Hematology/oncology clinics of North America · 2018
    Review
12. Turning the tide in myelodysplastic/myeloproliferative neoplasms.Nature reviews. Cancer · 2017
    Review
13. GATA2 deficiency and related myeloid neoplasms.Seminars in hematology · 2017
    Article
14. Codon-level co-occurrences of germline variants and somatic mutations in cancer are rare but often lead to incorrect variant annotation and underestimated impact prediction.PloS one · 2017
    Article
15. Mutational profiling of a MonoMAC syndrome family with GATA2 deficiency.Leukemia · 2017
    Article
16. The Role of Additional Sex Combs-Like Proteins in Cancer.Cold Spring Harbor perspectives in medicine · 2016
    Review
17. Leveraging premalignant biology for immune-based cancer prevention.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
18. Haematopoietic and immune defects associated with GATA2 mutation.British journal of haematology · 2015
    Review
19. Young woman with mild bone marrow dysplasia, GATA2 and ASXL1 mutation treated with allogeneic hematopoietic stem cell transplantation.Leukemia research reports · 2015
    Article
20. Co-mutation ofIn vivo (Athens, Greece)
    Article

Corrections and comments

• Comment on
  Acquired ASXL1 mutations are common in patients with inherited GATA2 mutations and correlate with myeloid transformation.2014

Authors and funding

2 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

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