Evidence map›Paper›PMID 24497504›Full record

ArticleBone & joint research2014

Basic science of anterior cruciate ligament injury and repair.

A M Kiapour, M M Murray

Registry-linked trialAbstract read
In one paragraph

Article in Bone & joint research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03670550 (Dynamic ACL Brace), which is not on this map. Cited by 127 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
127citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03670550 nawithdrawnnot on this mapstarted 2018, after this paper: background citation

Dynamic ACL Brace: In Vivo Kinematics

TypeinterventionalSponsorSteadman Philippon Research InstituteRan2018 to 2019Enrolled0ConditionsACL Injury, ACL - Anterior Cruciate Ligament Rupture, ACL, ACL - Anterior Cruciate Ligament DeficiencyArmsOssur Rebound ACL Brace
3 · Its place in the literature

Who cites it

127 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

67 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

A M KiapourBoston Children's Hospital, Harvard MedicalSchool, Sports Medicine Research Laboratory, Departmentof Orthopaedic Surgery, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.
M M Murray

Funding

Biologically Enhanced Healing of Autograft ACL Reconstruction.R01AR056834 · NIAMS · RHODE ISLAND HOSPITAL · PI FLEMING, BRADEN C, MURRAY, MARTHA M · 2009 to 2017
$5.8M
The Effect of Age on Functional ACL HealingR01AR054099 · NIAMS · BOSTON CHILDREN'S HOSPITAL · PI MURRAY, MARTHA M · 2006 to 2013
$4.8M
NIAMS NIH HHS R01 AR054099NIAMS NIH HHS R01 AR056834
6 · The paper itself

Abstract

Injury to the anterior cruciate ligament (ACL) is one of the most devastating and frequent injuries of the knee. Surgical reconstruction is the current standard of care for treatment of ACL injuries in active patients. The widespread adoption of ACL reconstruction over primary repair was based on early perception of the limited healing capacity of the ACL. Although the majority of ACL reconstruction surgeries successfully restore gross joint stability, post-traumatic osteoarthritis is commonplace following these injuries, even with ACL reconstruction. The development of new techniques to limit the long-term clinical sequelae associated with ACL reconstruction has been the main focus of research over the past decades. The improved knowledge of healing, along with recent advances in tissue engineering and regenerative medicine, has resulted in the discovery of novel biologically augmented ACL-repair techniques that have satisfactory outcomes in preclinical studies. This instructional review provides a summary of the latest advances made in ACL repair. Cite this article: Bone Joint Res 2014;3:20-31.

Indexed as

Anterior cruciate ligamentInjuryRepair

Identifiers

PMID24497504
PMCPMC3922117

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.