ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2015
A novel evaluation system to monitor bone formation and β-tricalcium phosphate resorption in opening wedge high tibial osteotomy.
Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 28 citations in OpenAlex.
- Novel unidirectional porous hydroxyapatite used as a bone substitute for open wedge high tibial osteotomy.Journal of materials science. Materials in medicine · 2014Trial
- Distal Tibial Oblique Osteotomy Combined with Strut Bone Allografting for the Treatment of Ankle Osteoarthritis with Varus Deformity: A Case Series.Journal of clinical medicine · 2026Article
- A review on the synthesis of β-TCP using different methods for biomedical applications.RSC advances · 2026Review
- Clinical evaluation of a novel cotton-like β-tricalcium phosphate, poly-L-lactic acid, and polyglycolic acid bone graft material for jawbone defects following cystectomy.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2026Article
- A case report of autogenous bone grafting using fibula regenerated from beta-tricalcium phosphate for a bone tumor: application of the in vivo bioreactor principle.BMC musculoskeletal disorders · 2026Article
- Update on synthetic biomaterials combined with fibrin derivatives for regenerative medicine: Applications in bone defect treatment: Systematic review.World journal of orthopedics · 2025Article
- Improvement of absorbability, osteoconductivity, and strength of a β-tricalcium phosphate spacer for opening wedge high tibial osteotomy: clinical evaluations with 106 patients.BMC musculoskeletal disorders · 2024Article
- Article
- Reconstruction of Load-Bearing Segmental Bone Defects Using Carbonate Apatite Honeycomb Blocks.ACS materials Au · 2023Article
- A Novel Quantitative Evaluation of Bone Formation After Opening Wedge High Tibial Osteotomy Using Tomosynthesis.Journal of digital imaging · 2022Article
- Combined use of beta-tricalcium phosphate with different porosities can accelerate bone remodelling in open-wedge high tibial osteotomy.Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology · 2022Article
- Distribution of hounsfield unit values in the pelvic bones: a comparison between young men and women with traumatic fractures and older men and women with fragility fractures: a retrospective cohort study.BMC musculoskeletal disorders · 2022Article
- Unidirectional porous beta-tricalcium phosphate and hydroxyapatite artificial bone: a review of experimental evaluations and clinical applications.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2021Review
- Local administration of HMGB-1 promotes bone regeneration on the critical-sized mandibular defects in rabbits.Scientific reports · 2021Article
- Use of unidirectional and spherical porous β-tricalcium phosphate in opening-wedge high tibial osteotomy: a case series.Journal of rural medicine : JRM · 2021Article
- A radiological study of bone remodeling with two different types of porous β-tricalcium phosphate in humans.Scientific reports · 2020Article
- A novel unidirectional porous β-tricalcium phosphate grafting for vertebral fracture in the elderly: preliminary case series.Journal of rural medicine : JRM · 2019Article
- Effects of micro-porosity and local BMP-2 administration on bioresorption of β-TCP and new bone formation.Biomaterials research · 2019Article
- An Injectable Complex of β-tricalcium Phosphate Granules, Hyaluronate, and rhFGF-2 on Repair of Long-bone Fractures with Large Fragments.The open biomedical engineering journal · 2014Article
- Tissue-engineered Maxillofacial Skeletal Defect Reconstruction by 3D Printed Beta-tricalcium phosphate Scaffold Tethered with Growth Factors and Fibrin Glue Implanted Autologous Bone Marrow-Derived Mesenchymal Stem Cells.Journal of medicine and lifeArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to establish an evaluation system to monitor bone formation and beta-tricalcium phosphate (TCP) resorption in opening high tibial osteotomy (HTO).
methodsFrom 2003 to 2005, opening HTO was performed in 36 patients using a Puddu plate and β-TCP blocks with 60 and 75 % porosity. Thirty-one patients were used for evaluation. All patients underwent CT examination at 2 weeks and 6 years. The CT image data were divided into three areas, and CT values of each area were analysed using the imaging software, Osirix.
resultsCT image analysis at 2 weeks showed that the mean CT-attenuation values (in Hounsfield units) of the implanted area with β-TCP of 60 % porosity, the implanted area with β-TCP of 75 % porosity, and cancellous bone were, 1,694.0 ± 94.2, 1,010.9 ± 81.1, and 178.0 ± 45.1, respectively. Six years after surgery, these values were 574.1 ± 273.5, 168.8 ± 75.1, and 174.9 ± 69.3, respectively.
conclusionβ-TCP with 75 % porosity was completely resorbed and replaced by bone. β-TCP with 60 % porosity was resorbed, but approximately 1/3 still remained even 6 years after surgery. The imaging software, Osirix, enabled scanning of the whole area to measure CT values. This system is the first to quantitatively evaluate β-TCP resorption and bone formation in opening HTO. LEVEL OF EVIDENCE: Laboratory studies.
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