Evidence map›Paper›PMID 24496667›Full record

ReviewAdvanced materials (Deerfield Beach, Fla.)2014

25th anniversary article: supramolecular materials for regenerative medicine.

Job Boekhoven, Samuel I Stupp

Abstract readReview
In one paragraph

Review in Advanced materials (Deerfield Beach, Fla.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

103 citing papers in PubMed.

  1. Injury and therapy in a human spinal cord organoid.Nature biomedical engineering · 2026
    Article
  2. Microengineered Gradient Hydrogels for Mechanobiology.Advanced healthcare materials · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Reciprocity in dynamics of supramolecular biosystems for the clustering of ligands and receptors.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Synthesis of Hybrid Peptide-Based Materials.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Detecting dynamic domains and local fluctuations in complex molecular systems via timelapse neighbors shuffling.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  20. Review

43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Job BoekhovenInstitute for BioNanotechnology in Medicine, Northwestern University, Chicago, Illinois, USA.
Samuel I Stupp

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniela E Matei · 1993 to 2026
$153.9M
Small Animal Surgery and HistologyP01HL108795 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LOSORDO, DOUGLAS W · 2011 to 2015
$10.7M
Regenerative Scaffold Technologies for CNS and DiabetesR01EB003806 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI STUPP, SAMUEL I · 2004 to 2015
$10.7M
Nanotechnology Strategies for Growth of Bones and TeethR01DE015920 · NIDCR · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SNEAD, MALCOLM L., STUPP, SAMUEL I · 2005 to 2015
$5.8M
NCI NIH HHS P30 CA060553NHLBI NIH HHS 1P01 HL108795NHLBI NIH HHS P01 HL108795NIBIB NIH HHS 5R01EB003806-08NIBIB NIH HHS R01 EB003806NIDCR NIH HHS 5R01DE015920-07NIDCR NIH HHS R01 DE015920
6 · The paper itself

Abstract

In supramolecular materials, molecular building blocks are designed to interact with one another via non-covalent interactions in order to create function. This offers the opportunity to create structures similar to those found in living systems that combine order and dynamics through the reversibility of intermolecular bonds. For regenerative medicine there is a great need to develop materials that signal cells effectively, deliver or bind bioactive agents in vivo at controlled rates, have highly tunable mechanical properties, but at the same time, can biodegrade safely and rapidly after fulfilling their function. These requirements make supramolecular materials a great platform to develop regenerative therapies. This review illustrates the emerging science of these materials and their use in a number of applications for regenerative medicine.

Indexed as

Regenerative MedicineAnimalsAnniversaries and Special EventsBiocompatible MaterialsHumansSignal TransductionTissue EngineeringBiocompatible Materialshealthcareregenerative medicineself-assemblysupramolecular materialstissue engineering

Identifiers

PMID24496667
PMCPMC4015801

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.