ArticleHead and neck pathology2015
Oral mucosal melanoma: some pathobiological considerations and an illustrative report of a case.
Article in Head and neck pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Hypomelanotic melanoma of the mandibular gingiva: a case report and literature review.BMC oral health · 2026Review
- Review
- Pigmented Fungiform Papillae (PFP) of the Tongue: A Systematic Review of Current Aetiopathogenesis and Pathophysiology.Pathophysiology : the official journal of the International Society for Pathophysiology · 2022Review
- Advances in the Understanding of Skin Cancer: Ultraviolet Radiation, Mutations, and Antisense Oligonucleotides as Anticancer Drugs.Molecules (Basel, Switzerland) · 2019Review
- Mucosal Melanoma: a Literature Review.Current oncology reports · 2018Review
- Rare and Extensive Malignant Melanoma of the Oral Cavity: Report of Two Cases.Journal of dentistry (Shiraz, Iran) · 2017Article
- Primary oral malignant melanoma metastasis to the brain and breast: A case report and literature review.Oncology letters · 2017Article
- A Review of the Aetiopathogenesis and Clinical and Histopathological Features of Oral Mucosal Melanoma.TheScientificWorldJournal · 2017Review
- Oral mucosal melanoma treated with carbon ion radiotherapy: a case report.Journal of medical case reports · 2016Article
- Basal cell carcinoma, squamous cell carcinoma and melanoma of the head and face.Head & face medicine · 2016Review
- Melanoma of the oral cavity: pathogenesis, dermoscopy, clinical features, staging and management.Journal of dermatological case reports · 2014Article
- Carcinoma of the lip five years after bone marrow transplantation.Annali di stomatologiaArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral mucosal melanoma is a relatively rare malignancy with an aggressive clinico-pathological behaviour. The mean 5-year survival rate is about 15 %. It arises primarily from melanocytes found in the basal cell layer of the epithelium, but may sometimes arise from melanocytes residing in the lamina propria. The pathogenesis is complex, and few of the molecular mechanisms underlying the development of oral mucosal melanoma have been defined. The extraneous risk factors associated with oral mucosal melanoma, if any, are unknown. Oral mucosal melanomas account for about 25 % of all mucosal melanomas of the head and neck, and exhibit a profile of cytogenetic alterations, and a pathobiological behaviour and clinical course different from that of cutaneous melanomas. As they are usually painless and grow quickly, as a rule, they are diagnosed late in the course of the disease when the lesions are already large and have metastasized to regional lymph nodes. In this paper we discuss some aspects of the pathobiology of oral mucosal melanoma, and present an illustrative case report.
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