ArticlePrimary care respiratory journal : journal of the General Practice Airways Group2014
Predicting asthma in preschool children at high risk presenting in primary care: development of a clinical asthma prediction score.
Article in Primary care respiratory journal : journal of the General Practice Airways Group, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Risk Factors in Preschool Children for Predicting Asthma During the Preschool Age and the Early School Age: a Systematic Review and Meta-Analysis.Current allergy and asthma reports · 2017Pooled it
- Atopic dermatitis, asthma and allergic rhinitis in general practice and the open population: a systematic review.Scandinavian journal of primary health care · 2016Pooled it
- A systematic review of predictive models for asthma development in children.BMC medical informatics and decision making · 2015Pooled it
- Early-life prediction of school-age asthma among recurrent Wheezers in preschoolers: The WHEEP study.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025Article
- Prediction of adult asthma risk in early childhood using novel adult asthma predictive risk scores.Allergy · 2023Article
- Article
- Why Is It Difficult to Diagnose My Child's Asthma? A Patient Physician Perspective of Asthma Management.Pulmonary therapy · 2019Article
- Preschool Wheezing Phenotypes Exhibit Heterogeneity in Disease Expression and Prognosis.Annals of the American Thoracic Society · 2019Article
- Predicting Teen Dating Violence Perpetration.Pediatrics · 2018Article
- A young child with a history of wheeze.NPJ primary care respiratory medicine · 2017Article
- The Role of Sensitization to Allergen in Asthma Prediction and Prevention.Frontiers in pediatrics · 2017Review
- Factors predicting persistence of early wheezing through childhood and adolescence: a systematic review of the literature.Journal of asthma and allergy · 2017Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA setting-specific asthma prediction score for preschool children with wheezing and/or dyspnoea presenting in primary healthcare is needed since existing indices are mainly based on general populations.
aimsTo find an optimally informative yet practical set of predictors for the prediction of asthma in preschool children at high risk who present in primary healthcare.
methodsA total of 771 Dutch preschool children at high risk of asthma were followed prospectively until the age of six years. Data on asthma symptoms and environmental conditions were obtained using validated questionnaires and specific IgE was measured. At the age of six years the presence of asthma was assessed based on asthma symptoms, medication, and bronchial hyper-responsiveness. A clinical asthma prediction score (CAPS) was developed using bootstrapped multivariable regression methods.
resultsIn all, 438 children (56.8%) completed the study; the asthma prevalence at six years was 42.7%. Five parameters optimally predicted asthma: age, family history of asthma or allergy, wheezing-induced sleep disturbances, wheezing in the absence of common colds, and specific IgE. CAPS scores range from 0 to 11 points; scores <3 signified a negative predictive value of 78.4% while scores of >7 signified a positive predictive value of 74.3%.
conclusionsWe have developed an easy-to-use CAPS for preschool children with symptoms suggesting asthma who present in primary healthcare. After suitable validation, the CAPS may assist in guiding shared decision-making to tailor the need for medical or non-medical interventions. External validation of the CAPS is needed.
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