ArticleJournal of polymer science. Part A, Polymer chemistry2013
Modeling Controlled Photodegradation in Optically Thick Hydrogels.
Article in Journal of polymer science. Part A, Polymer chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- On-Demand Photodegradable and Thermo-Reversible, Soft, Transparent Dithioacetal Hydrogels.Angewandte Chemie (International ed. in English) · 2025Article
- Photodegradable polyacrylamide tanglemers enable spatiotemporal control over chain lengthening in high-strength and low-hysteresis hydrogels.Journal of materials chemistry. B · 2025Article
- Gelation Dynamics during Photo-Cross-Linking of Polymer Nanocomposite Hydrogels.ACS polymers Au · 2023Article
- Spatiotemporal patterning of photoresponsive DNA-based hydrogels to tune local cell responses.Nature communications · 2021Article
- Environment Controls Biomolecule Release from Dynamic Covalent Hydrogels.Biomacromolecules · 2021Article
- On-demand and tunable dual wavelength release of antibody using light-responsive hydrogels.ACS applied bio materials · 2020Article
- Spatiotemporally Controlled Photoresponsive Hydrogels: Design and Predictive Modeling from Processing through Application.Advanced functional materials · 2020Review
- Dynamic Supramolecular Ruthenium-Based Gels Responsive to Visible/NIR Light and Heat.Chemistry (Weinheim an der Bergstrasse, Germany) · 2019Article
- From Microscale to Macroscale: Nine Orders of Magnitude for a Comprehensive Modeling of Hydrogels for Controlled Drug Delivery.Gels (Basel, Switzerland) · 2019Review
- Immunofunctional photodegradable poly(ethylene glycol) hydrogel surfaces for the capture and release of rare cells.Colloids and surfaces. B, Biointerfaces · 2019Article
- Spatiotemporal hydrogel biomaterials for regenerative medicine.Chemical Society reviews · 2017Review
- Spatially and Temporally Controlled Hydrogels for Tissue Engineering.Materials science & engineering. R, Reports : a review journal · 2017Article
- On-demand dissolution of modular, synthetic extracellular matrix reveals local epithelial-stromal communication networks.Biomaterials · 2017Article
- Amplified Photodegradation of Cell-Laden Hydrogels via an Addition-Fragmentation Chain Transfer Reaction.Advanced materials (Deerfield Beach, Fla.) · 2017Article
- Design of Thiol- and Light-sensitive Degradable Hydrogels using Michael-type Addition Reactions.Polymer chemistry · 2015Article
- Stimulus-responsive hydrogels: Theory, modern advances, and applications.Materials science & engineering. R, Reports : a review journal · 2015Article
- Mechanical memory and dosing influence stem cell fate.Nature materials · 2014Article
- Clickable, photodegradable hydrogels to dynamically modulate valvular interstitial cell phenotype.Advanced healthcare materials · 2014Article
- Hydrogels preserve native phenotypes of valvular fibroblasts through an elasticity-regulated PI3K/AKT pathway.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Mechanical Properties and Degradation of Chain and Step Polymerized Photodegradable Hydrogels.Macromolecules · 2013Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
There is a growing interest in developing dynamically responsive hydrogels whose material properties are modulated by environmental cues, including with light. These photoresponsive hydrogels afford spatiotemporal control of material properties through an array of photoaddition and photodegradation reactions. For photoresponsive hydrogels to be utilized most effectively in a broad range of applications, the photoreaction behavior should be well understood, enabling the design of dynamic materials with uniform or anisostropic material properties. Here, a general statistical-kinetic model has been developed to describe controlled photodegradation in hydrogel polymer networks containing photolabile crosslinks. The heterogeneous reaction rates that necessarily accompany photochemical reactions were described by solving a system of partial differential equations that quantify the photoreaction kinetics in the material. The kinetics were coupled with statistical descriptions of network structure in chain polymerized hydrogels to model material property changes and mass loss that occur during the photodegradation process. Finally, the physical relevance of the model was demonstrated by comparing model predictions with experimental data of mass loss and material property changes in photodegradable, PEG-based hydrogels.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.