Evidence map›Paper›PMID 24496473›Full record

ArticleChemical communications (Cambridge, England)2014

Fluorous enzymatic synthesis of phosphatidylinositides.

Weigang Huang, Angela Proctor, Christopher E Sims, Nancy L Allbritton, Qisheng Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical communications (Cambridge, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Weigang HuangDivision of Chemical Biology and Medicinal Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. qszhang@unc.edu.
Angela Proctor
Christopher E Sims
Nancy L Allbritton
Qisheng Zhang
University of North Carolina at Chapel Hill · USCommunities In Schools of Orange County · USInstitute of Medicinal Plant Development · CN

Funding

Multiplexed Measurement of Kinase Activity in Single Cancer CellsR01CA139599 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ALLBRITTON, NANCY L. · 2009 to 2013
$2.7M
High-throughput screens to identify modulators of phospholipase C isozymesR01GM098894 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SONDEK, JOHN E, ZHANG, QISHENG · 2011 to 2013
$834k
NCI NIH HHS CA139599NCI NIH HHS R01 CA139599NIGMS NIH HHS GM098894NIGMS NIH HHS R01 GM098894
6 · The paper itself

Abstract

A fluorous tagging strategy coupled with enzymatic synthesis is introduced to efficiently synthesize multiple phosphatidylinositides, which are then directly immobilized on a fluorous polytetrafluoroethylene (PTFE) membrane to probe protein-lipid interactions.

Indexed as

AntibodiesFluorescent DyesPhosphatidylinositol 3-KinasesPhosphatidylinositolsPolytetrafluoroethyleneProtein Array AnalysisType C PhospholipasesAntibodiesFluorescent DyesPhosphatidylinositol 3-KinasesPhosphatidylinositolsPolytetrafluoroethyleneType C Phospholipases

Identifiers

PMID24496473
PMCPMC3993006
OpenAlexW2023799571

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.