ArticleComparative biochemistry and physiology. Toxicology & pharmacology : CBP2014
Characterization and differential expression of CPD and 6-4 DNA photolyases in Xiphophorus species and interspecies hybrids.
Article in Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 34 citations in OpenAlex.
- Validity of Xiphophorus fish as models for human disease.Disease models & mechanisms · 2024Review
- Global assessment of organ specific basal gene expression over a diurnal cycle with analyses of gene copies exhibiting cyclic expression patterns.BMC genomics · 2020Article
- Comparison of Xiphophorus and human melanoma transcriptomes reveals conserved pathway interactions.Pigment cell & melanoma research · 2018Article
- Fluorescent light exposure incites acute and prolonged immune responses in zebrafish (Danio rerio) skin.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2018Article
- Exposure to 4100K fluorescent light elicits sex specific transcriptional responses in Xiphophorus maculatus skin.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2018Article
- The transcriptional response of skin to fluorescent light exposure in viviparous (Xiphophorus) and oviparous (Danio, Oryzias) fishes.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2018Article
- Characterization of basal gene expression trends over a diurnal cycle in Xiphophorus maculatus skin, brain and liver.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2018Article
- Waveband specific transcriptional control of select genetic pathways in vertebrate skin (Xiphophorus maculatus).BMC genomics · 2018Article
- Molecular genetic analysis of the melanoma regulatory locus in Xiphophorus interspecies hybrids.Molecular carcinogenesis · 2017Article
- Exposure to fluorescent light triggers down regulation of genes involved with mitotic progression in Xiphophorus skin.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2015Article
- Sex-specific molecular genetic response to UVB exposure in Xiphophorus maculatus skin.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2015Article
- Molecular genetic response to varied wavelengths of light in Xiphophorus maculatus skin.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2015Article
- Molecular genetic response of Xiphophorus maculatus-X. couchianus interspecies hybrid skin to UVB exposure.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2015Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Among the many Xiphophorus interspecies hybrid tumor models are those that exhibit ultraviolet light (UVB) induced melanoma. In previous studies, assessment of UVB induced DNA damage and nucleotide excision DNA repair has been performed in parental lines and interspecies hybrids. Species and hybrid specific differences in the levels of DNA damage induced and the dark repair rates for cyclobutane pyrimidine dimers (CPDs) and 6-4 pyrimidine pyrimidine photoproducts (6-4PPs) have been reported. However, UVB induced DNA lesions in Xiphophorus fishes are thought to primarily be repaired via light dependent CPD and 6-4PP specific photolyases. Photolyases are of evolutionary interest since they are ancient and presumably function solely to ameliorate the deleterious effects of UVB exposure. Herein, we report results from detailed studies of CPD and 6-4PP photolyase gene expression within several Xiphophorus tissues. We determined photolyase gene expression patterns before and after exposure to fluorescent light in X. maculatus, X. couchianus, and for F1 interspecies hybrids produced from crossing these two parental lines (X. maculatus Jp 163 B×X. couchianus). We present novel results showing these two photolyase genes exhibit species, tissue, and hybrid-specific differences in basal and light induced gene expression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.