Evidence map›Paper›PMID 24495921›Full record

ArticleScientific reports2014

Limited geographic distribution of the novel cyclovirus CyCV-VN.

Van Tan Le, Menno D de Jong, Van Kinh Nguyen, Vu Trung Nguyen, Walter Taylor, Heiman F L Wertheim, Arie van der Ende, Lia van der Hoek, Marta Canuti, Martin Crusat and 10 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Highly Sensitive Virome Characterization ofPathogens (Basel, Switzerland) · 2020
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 9 institutions in 5 countries.

Van Tan LeOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Menno D de Jong1] Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam [2] Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Van Kinh Nguyen1] National Hospital for Tropical Diseases, Hanoi, Vietnam [2] Hanoi Medical University, Hanoi, Vietnam.
Vu Trung Nguyen1] National Hospital for Tropical Diseases, Hanoi, Vietnam [2] Hanoi Medical University, Hanoi, Vietnam.
Walter Taylor1] Oxford University Clinical Research Unit, Hanoi, Vietnam [2] Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Heiman F L Wertheim1] Oxford University Clinical Research Unit, Hanoi, Vietnam [2] Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Arie van der Ende1] Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands [2] The Netherlands National Reference Laboratory for Bacterial Meningitis, Amsterdam, the Netherlands.
Lia van der HoekDepartment of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Marta CanutiDepartment of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Martin CrusatDepartment of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Soeng SonaAngkor Hospital for Children, Siem Reap, Kingdom of Cambodia.
Hanh Uyen NguyenOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Abhishek GiriOxford University Clinical Research Unit, Patan Hospital, Kathmandu, Nepal.
Thi Thuy Chinh Bkrong NguyenOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Dang Trung Nghia Ho1] Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam [2] Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam [3] Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.
Jeremy Farrar1] Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam [2] Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Juliet E Bryant1] Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam [2] Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Tinh Hien Tran1] Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam [2] Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Van Vinh Chau NguyenPham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.
H Rogier van Doorn1] Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam [2] Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Oxford University Clinical Research Unit · VNUniversity of Oxford · GBAcademic Medical Center · NLUniversity of Amsterdam · NLAngkor Hospital for Children · KHHanoi Medical University · VNHospital for Tropical Diseases · VNPatan Hospital · NPPham Ngoc Thach University of Medicine · VN

Funding

Wellcome Trust 089276/Z/09/ZWellcome Trust 093724/Z/10/ZWellcome Trust 101104Wellcome Trust 101104/Z/13/Z
6 · The paper itself

Abstract

A novel cyclovirus, CyCV-VN, was recently identified in cerebrospinal fluid (CSF) from patients with central nervous system (CNS) infections in central and southern Vietnam. To explore the geographic distribution of this novel virus, more than 600 CSF specimens from patients with suspected CNS infections in northern Vietnam, Cambodia, Nepal and The Netherlands were screened for the presence of CyCV-VN but all were negative. Sequence comparison and phylogenetic analysis between CyCV-VN and another novel cyclovirus recently identified in CSF from Malawian patients indicated that these represent distinct cycloviral species, albeit phylogenetically closely related. The data suggest that CyCV-VN has a limited geographic distribution within southern and central Vietnam. Further research is needed to determine the global distribution and diversity of cycloviruses and importantly their possible association with human disease.

Indexed as

AdultBase SequenceCentral Nervous System InfectionsChildCircoviridaeCircoviridae InfectionsDNA, ViralFemaleGenetic VariationGenome, ViralGeographyHumansMalawiMaleMolecular Sequence DataSequence AlignmentDNA, Viral

Identifiers

PMID24495921
PMCPMC3913916
OpenAlexW2052743525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.