Evidence map›Paper›PMID 24494173›Full record

ArticleJournal of biochemical and pharmacological research2013

Homozygous Deletion of Glutathione Peroxidase 1 and Aldehyde Dehydrogenase 1a1 Genes Is Not Associated with Schizophrenia-Like Behavior in Mice.

Xiang Bai, Elizabeth Fermandez, Georgianna Gould, Randy Strong

Open access · greenAbstract read
In one paragraph

Article in Journal of biochemical and pharmacological research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Xiang BaiDepartment of Pharmacology, University of Texas Health Science Center, San Antonio, TX USA ; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, TX USA.
Elizabeth FermandezDepartment of Pharmacology, University of Texas Health Science Center, San Antonio, TX USA ; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, TX USA ; Geriatric Research, Education and Clinical Center, South Texas Veterans Health Care Network, San Antonio, TX USA.
Georgianna GouldDepartment of Physiology, South Texas Veterans Health Care Network, San Antonio, TX USA.
Randy StrongDepartment of Pharmacology, University of Texas Health Science Center, San Antonio, TX USA ; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, TX USA ; Geriatric Research, Education and Clinical Center, South Texas Veterans Health Care Network, San Antonio, TX USA.
The University of Texas Health Science Center at San Antonio · USSouth Texas Veterans Health Care System · US

Funding

TRANSGENIC COREP30AG013319 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI JAMES FLOYD NELSON · 1995 to 2026
$30.6M
OCT Blockade to Restore Sociability in 5-HT Transporter Knock-Out MiceR03MH086708 · NIMH · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI GOULD, GEORGIANNA G. · 2011 to 2012
$149k
Detoxification of Biogenic Aldehydes in Parkinson's DiseaseI01BX001641 · VA · SOUTH TEXAS VETERANS HEALTH CARE SYSTEM · PI STRONG, RANDY · 2013 to 2023
–
BLRD VA I01 BX001641NIA NIH HHS P30 AG013319NIMH NIH HHS R03 MH086708
6 · The paper itself

Abstract

Much evidence suggests that oxidative stress plays a role in schizophrenia pathogenesis. Major oxidative stress sources include hydrogen peroxide and biogenic aldehydes that are mainly cleared

Indexed as

aldehyde dehydrogenase 1a1 (Aldh1a1)gene deletionglutathione peroxidase 1 (Gpx1)oxidative stressschizophrenia

Identifiers

PMID24494173
PMCPMC3909525
OpenAlexW2112712674

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.