ArticleDermato-endocrinology2013
What is the relationship between ultraviolet B and global incidence rates of colorectal cancer?
Article in Dermato-endocrinology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed.
- Could age increase the strength of inverse association between ultraviolet B exposure and colorectal cancer?BMC public health · 2021Article
- Vitamin D deficiency in theDisease models & mechanisms · 2018Article
- Sunlight and Vitamin D: Necessary for Public Health.Journal of the American College of Nutrition · 2015Article
- Low Cloud Cover-Adjusted Ultraviolet B Irradiance Is Associated with High Incidence Rates of Leukemia: Study of 172 Countries.PloS one · 2015Article
- A multicountry ecological study of cancer incidence rates in 2008 with respect to various risk-modifying factors.Nutrients · 2013Observational
- Solar radiation and the incidence and mortality of leading invasive cancers in the United States.Dermato-endocrinologyArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study is to examine the relationship between ultraviolet B and global incidence of colorectal cancer, while controlling for relevant covariates. Linear regression was used to assess the relationship between latitude and incidence rates of colon cancer in 173 countries. Multiple linear regression was employed to investigate the relationship between ultraviolet B dose and colorectal cancer rates while controlling for per capita intake of energy from animal sources, per capita health expenditure, pigmentation, and life expectancy. Data on all variables were available for 139 countries. Incidence of colon cancer was highest in countries distant from the equator (R(2) = 0.50, p < 0.0001). UV B dose (p < 0.0001) was independently, inversely associated with incidence rates of colorectal cancer after controlling for intake of energy from animal sources, per capita health expenditure, pigmentation, and life expectancy (R(2) for overall model = 0.76, p < 0.0001). Consistent with previous research, UVB was inversely associated with incidence of colon cancer. Further research on vitamin D and prevention of colon cancer in individuals should be conducted, including studies of higher serum 25-hydroxyvitamin D concentrations than have been studied to date.
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