Evidence map›Paper›PMID 24494046›Full record

ArticleDermato-endocrinology2013

Vitamin D status and sun exposure in India.

Chittari V Harinarayan, Michael F Holick, Upadrasta V Prasad, Palavali S Vani, Gutha Himabindu

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Dermato-endocrinology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04986319 (The Level of Serum Vitamin D And Parathyroid Hormone Among Different Bangladeshi Population Groups), which is not on this map. Cited by 56 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 4 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04986319 completednot on this mapstarted 2017, after this paper: background citation

The Level of Serum Vitamin D And Parathyroid Hormone Among Different Bangladeshi Population Groups

TypeobservationalSponsorBangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic DisordersRan2017 to 2021Enrolled556ConditionsVitamin D DeficiencyArmsSerum vitamin D assay
3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 4 syntheses or guidelines pooled it, 140 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 4 countries.

Chittari V HarinarayanDepartment of Endocrinology and Metabolism; Sri Venkateswara Institute of Medical Sciences; Tirupati; Andhra Pradesh, India.
Michael F HolickDepartment of Medicine, Section of Endocrinology, Nutrition, and Diabetes Vitamin D; Skin and Bone Research Laboratory; Boston University Medical Center; Boston University School of Medicine; Boston, MA USA.
Upadrasta V PrasadDepartment of Endocrinology and Metabolism; Sri Venkateswara Institute of Medical Sciences; Tirupati; Andhra Pradesh, India.
Palavali S VaniDepartment of Endocrinology and Metabolism; Sri Venkateswara Institute of Medical Sciences; Tirupati; Andhra Pradesh, India.
Gutha HimabinduDepartment of Endocrinology and Metabolism; Sri Venkateswara Institute of Medical Sciences; Tirupati; Andhra Pradesh, India.
Sri Venkateswara Institute of Medical Sciences · INBoston University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLittle if any cutaneous production of vitamin D3 occurs at latitudes above and below 35° N and 35° S during the winter months. It was postulated that those residing in tropics synthesize enough vitamin D3 year round. Several studies have documented the effect of latitude, season and time of the day on the cutaneous production of vitamin D3 in an ampoule model. Studies from India have shown high prevalence of vitamin D deficiency despite abundant sunshine.

methodsWe studied the influence of season and time of the day on synthesis of previtamin D3 in an ampoule model in Tirupati, (latitude 13.40° N and longitude 77.2° E) south India, between May 2007 to August 2008. Sealed borosilicate glass ampoules containing 50 μg of 7-DHC in 1 ml of methanol were exposed to sunlight hourly from 8 a.m. until 4 p.m. The percent conversion of 7-DHC to previtamin D3 and its photoproducts and the percent of previtamin D3 and vitamin D3 formed was estimated and related to solar zenith angle.

resultsThe percent conversion of 7-DHC to previtamin D3 and its photoproducts and formation of previtamin D3 and vitamin D3 was maximal between 11 a.m. to 2 p.m. of the day during the entire year (median 11.5% and 10.2% respectively at 12.30 p.m.).

conclusionsTherefore at this latitude exposure to sunlight between the hours of 11 a.m. and 2 p.m. will promote vitamin D production in the skin year round.

Indexed as

7-dehydrocholesterol (7-DHC)Indiaprevitamin D3sun exposurevitamin D3zenith angle

Identifiers

PMID24494046
PMCPMC3897581
OpenAlexW1964898003

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.