ArticleClinical and experimental immunology1987
Antibodies to basement membrane proteins nidogen and laminin in sera from streptococcal-related diseases and juvenile rheumatoid arthritis patients.
Article in Clinical and experimental immunology, 1987. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 13 citations in OpenAlex.
- Antibodies to mouse laminin in patients with systemic sclerosis (scleroderma) recognize galactosyl (alpha 1-3)-galactose epitopes.Clinical and experimental immunology · 1991Trial
- Anti-laminin autoantibodies in collagen vascular diseases: the use of adequate controls in studies of autoimmune responses to laminin.Annals of the rheumatic diseases · 1994Article
- Antibodies to laminin and immunohistochemical localization of laminin in chronic chagasic cardiomyopathy: a review.Molecular and cellular biochemistry · 1993Article
- Anti-IgG antibodies in rheumatic diseases cross-react with Streptococcus mutans SR antigen.Clinical and experimental immunology · 1991Article
- Persistence of elevated levels of galactosyl-alpha(1-3)galactose antibodies in sera from patients cured of visceral leishmaniasis.Journal of clinical microbiology · 1988Article
- Elevated IgG autoantibody production in oligoarticular juvenile idiopathic arthritis may predict a refractory course.Clinical and experimental rheumatologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Using the ELISA technique, antibodies against two different basement proteins, laminin and nidogen (ALNA), were determined in 226 children suffering from one of 37 different inflammatory or infectious diseases. These included 80 patients with streptococcal infection and 40 with juvenile rheumatoid arthritis. Forty-eight percent of the streptococcus-infected patients (or 75% of those in the acute phase) and 60% of juvenile rheumatoid arthritis patients had significantly elevated ALNA levels compared with healthy controls. Interestingly 10 adult rheumatoid arthritis patients displayed normal ALNA levels, suggesting a particular immune process occurring in children affected by juvenile rheumatoid arthritis. By means of periodate oxidation and glycosidase treatments we have shown that ALNA positive sera recognized terminal alpha-galactose as the reactive epitope.
Indexed as
Identifiers
2449305PMC1542183W2398772593What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.