Evidence map›Paper›PMID 24491807›Full record

ArticleInternational journal of pediatric otorhinolaryngology2014

Eustachian tube opening measured by sonotubometry is poorer in adults with a history of past middle ear disease.

Miriam S Teixeira, Juliane Banks, J Douglas Swarts, Cuneyt M Alper, William J Doyle

Abstract readComparative StudyControlled Clinical Trial
In one paragraph

Article in International journal of pediatric otorhinolaryngology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Advances in Eustachian tube function testing.World journal of otorhinolaryngology - head and neck surgery · 2019
    Review
  10. Article
  11. Accuracy of the ETDQ-7 for Identifying Persons with Eustachian Tube Dysfunction.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2018
    Article
  12. Observational
  13. Eustachian Tube Function in 6-Year-Old Children with and without a History of Middle Ear Disease.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2016
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Miriam S TeixeiraDepartment of Otolaryngology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA. Electronic address: teixeirams@upmc.edu.
Juliane BanksDepartment of Otolaryngology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA.
J Douglas SwartsDepartment of Otolaryngology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA.
Cuneyt M AlperDepartment of Otolaryngology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA.
William J DoyleDepartment of Otolaryngology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA.
University of Pittsburgh · US

Funding

Testing/ImagingP50DC007667 · NIDCD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ALPER, CUNEYT METIN · 2006 to 2017
$12.6M
NIDCD NIH HHS P50 DC007667
6 · The paper itself

Abstract

objectiveTest the hypothesis that active Eustachian tube opening efficiency as measured by sonotubometry is higher in adults with no extant middle-ear disease and no history of previous otitis media (Group-1) when compared to adults with no middle-ear disease but a positive history for otitis media (Group-2).

methodsEustachian tube function for 1 ear of 33 otherwise healthy adult subjects, 16 assigned to Group-1 and 17 to Group-2, was tested by sonotubometry using a standard protocol. For each test, the sound envelopes for 3 swallows were abstracted independently by 2 observers from the data stream and 7 descriptive parameters related to sound envelope "shape" were calculated. Inter-relatedness among the values for the parameters was explored using correlation analysis. The contributions of swallow, observer and group to the variance in each parameter were evaluated for significance using a General Linear Model.

resultsThe shape parameters reflecting envelope height, area and rise and fall rates were highly inter-correlated, but those reflecting envelope widths were not. There was no effect of "swallow" on any of the parameters; but there was a significant "observer" effect on all measures of envelope width, greater for observer-2, and a significant "group" effect for 5 of the 7 shape parameters, all greater in Group-1.

conclusionsQuantifiable measures of the sound signal "shape" recorded by sonotubometry during swallowing were significantly different between the 2 groups of subjects. This is interpretable as evidencing a more efficient Eustachian tube opening-function in adults with healthy middle ears who do not have a previous history of otitis media when compared to similar adults with a history of prior otitis media. Inefficient Eustachian tube function as children may not be completely resolved by adulthood increasing adult otitis media risk when Eustachian tube function is down-graded by extant upper respiratory diseases that provoke nasopharyngeal inflammation.

Indexed as

Diagnostic Techniques, OtologicalAcoustic Impedance TestsAdolescentAdultAge FactorsCase-Control StudiesConstriction, PathologicDeglutitionEustachian TubeFemaleHumansMaleMiddle AgedMiddle Ear VentilationOtitis Media with EffusionPrognosisAdultsEustachian tubeMethodologyOtitis mediaOtitis media riskSonotubometry

Identifiers

PMID24491807
PMCPMC4017584
OpenAlexW2065905164

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.