Evidence map›Paper›PMID 24491689›Full record

ArticleJournal of the American College of Cardiology2014

The global health and economic burden of hospitalizations for heart failure: lessons learned from hospitalized heart failure registries.

Andrew P Ambrosy, Gregg C Fonarow, Javed Butler, Ovidiu Chioncel, Stephen J Greene, Muthiah Vaduganathan, Savina Nodari, Carolyn S P Lam, Naoki Sato, Ami N Shah and 1 more

8 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in Journal of the American College of Cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 8 registered trials, which are not on this map. Cited by 957 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
957citing papers in PubMed, 11 pooled it
81.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06097585 unknown statusstarted 2023, after this paper: background citation

Effect of Gliflozins on Heart Failure Due to Regurgitant Rheumatic Valve Disease

Ran2023Enrolled150Registered outcomes5Posted comparisons0ConditionsHeart Failure, Rheumatic Heart DiseaseArmsSGLT2 inhibitor
Open the trial in the graph
NCT03579641 completednot on this mapstarted 2018, after this paper: background citation

Precision Event Monitoring for Patients With Heart Failure Using HeartLogic: PREEMPT-HF

TypeobservationalSponsorBoston Scientific CorporationRan2018 to 2021Enrolled2,184ConditionsHeart Failure, Defibrillators, Implantable, Monitoring, Physiologic, Cardiac Resynchronization TherapyArmsHeartLogic Sensors
NCT04189029 unknown statusnot on this mapstarted 2019, after this paper: background citation

Redefining the Phenotypic Spectrum of Heart Failure With Preserved Ejection Fraction (HFpEF) by Deep Phenotyping and Machine Learning Methods: The PACIFIC-PRESERVED Study (PhenomApping, ClassIFication, and Innovation for Cardiac Dysfunction - HF With PRESERVED LVEF Study)

Typeobservational_patient_registrySponsorAssistance Publique - Hôpitaux de ParisRan2019 to 2025Enrolled175ConditionsHeart Failure, Heart Failure With Preserved Ejection FractionArmsExtensive phenotyping
NCT04806048 completednot on this mapstarted 2021, after this paper: background citation

Feasibility of the Use in Spanish Hospitals of Recommended Standards to Measure Results in Patients With Heart Failure (HF-Outcomes-Spain)

TypeobservationalSponsorFundación Pública Galega de Investigación Biomédica INIBICRan2021 to 2022Enrolled581ConditionsHeart Failure
NCT04882449 completednot on this mapstarted 2021, after this paper: background citation

Surveillance and Alert-based Multiparameter Monitoring to Reduce Worsening Heart Failure Events - SCALE-HF1

TypeobservationalSponsorBodyport Inc.Ran2021 to 2023Enrolled329ConditionsHeart FailureArmsBodyport Cardiac Scale
NCT05467735 naterminatednot on this mapstarted 2022, after this paper: background citation

Above-Knee-High Application of Lower Limb Compression and Its Impact on Clinical Outcome in Patients Hospitalized With Heart Failure Exacerbation.

TypeinterventionalSponsorThe University of Texas Medical Branch, GalvestonRan2022 to 2024Enrolled20ConditionsHeart Failure, With Decompensation, Lower Extremity Edema, Heart Failure,CongestiveArmsApplication of compression to bilateral lower extremities of patients using appropriately-sized elastic compression stockings.
NCT06447467 unknown statusnot on this mapstarted 2024, after this paper: background citation

Short Term Outcome of Acute Heart Failure in Diabetic and Non Diabetic Patients

TypeobservationalSponsorSohag UniversityRan2024 to 2024Enrolled100ConditionsAcute Heart Failure, Diabetes MellitusArmspro BNP
NCT06554912 nawithdrawnnot on this mapstarted 2024, after this paper: background citation

Evaluation of Safety and Feasibility of Lymphatic Decompression in Chronic Heart Failure

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2024 to 2024Enrolled0ConditionsCardiovascular Diseases, Chronic Heart FailureArmsLymphatic Decompression
3 · Its place in the literature

Who cites it

957 citing papers in PubMed, 11 syntheses or guidelines pooled it, 1,999 citations in OpenAlex.

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  18. An integrated overview of acute heart failure: a narrative review of pathophysiological mechanisms and contributing factors.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026
    Review
  19. Heart failure burden and care among cardiology inpatients: insights from the Hellenic Cardiorenal Morbidity Snapshot (HECMOS) study.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  20. Observational

897 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 4 countries.

Andrew P AmbrosyDepartment of Medicine, Stanford University School of Medicine, Palo Alto, California.
Gregg C FonarowAhmanson-UCLA Cardiomyopathy Center, Ronald Reagan-UCLA Medical Center, Los Angeles, California.
Javed ButlerDivision of Cardiology, Emory University, Atlanta, Georgia.
Ovidiu ChioncelInstitute of Emergency for Cardiovascular Diseases Prof. C.C. Iliescu, Cardiology 1, Bucharest, Romania.
Stephen J GreeneCenter for Cardiovascular Innovation, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Muthiah VaduganathanDepartment of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Savina NodariDepartment of Cardiology, University of Brescia, Brescia, Italy.
Carolyn S P LamNational University Health Centre, Singapore.
Naoki SatoInternal Medicine, Cardiology, and Intensive Care Medicine, Nippon Medical School Musashi-Kosugi Hospital, Kanagawa, Japan.
Ami N ShahCenter for Cardiovascular Innovation, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Mihai GheorghiadeCenter for Cardiovascular Innovation, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Electronic address: mgheorghiade@nmff.org.
Northwestern University · USEmory University · USHarvard University · USInstitutul de Urgenţă pentru Boli Cardiovasculare "Prof.Dr. C.C. Iliescu" · RONippon Medical School Musashi Kosugi Hospital · JPRonald Reagan UCLA Medical Center · USStanford University · USUniversity of Brescia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart failure is a global pandemic affecting an estimated 26 million people worldwide and resulting in more than 1 million hospitalizations annually in both the United States and Europe. Although the outcomes for ambulatory HF patients with a reduced ejection fraction (EF) have improved with the discovery of multiple evidence-based drug and device therapies, hospitalized heart failure (HHF) patients continue to experience unacceptably high post-discharge mortality and readmission rates that have not changed in the last 2 decades. In addition, the proportion of HHF patients classified as having a preserved EF continues to grow and may overtake HF with a reduced EF in the near future. However, the prognosis for HF with a preserved EF is similar and there are currently no available disease-modifying therapies. HHF registries have significantly improved our understanding of this clinical entity and remain an important source of data shaping both public policy and research efforts. The authors review global HHF registries to describe the patient characteristics, management, outcomes and their predictors, quality improvement initiatives, regional differences, and limitations of the available data. Moreover, based on the lessons learned, they also propose a roadmap for the design and conduct of future HHF registries.

Indexed as

HospitalizationRegistriesAdrenergic beta-AntagonistsAgedAge DistributionAnemiaAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsAsiaCardiac Resynchronization TherapyCardiotonic AgentsCatheterization, Swan-GanzComorbidityCoronary AngiographyDefibrillators, ImplantableDiureticsAdrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsCardiotonic AgentsDiureticsMineralocorticoid Receptor AntagonistsNatriuretic PeptidesVasodilator Agentsacuteheart failurehospitalizationinpatientregistry

Identifiers

PMID24491689
OpenAlexW59066530

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 2 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.