Trial reportJournal of consulting and clinical psychology2014
Mindfulness-oriented recovery enhancement for chronic pain and prescription opioid misuse: results from an early-stage randomized controlled trial.
Trial report in Journal of consulting and clinical psychology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 184 papers, 13 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Mission Reconnect: Delivering a Mobile and Web Based Self Directed Complementary and Integrative Health Program to Veterans and Their Partners to Manage Pain and PTSD
Reating Opioid Misuse Via Mindfulness-Based Just-in-Time Adaptive Intervention
Randomized Trial of Acceptance and Commitment Therapy (ACT) and a Care Management App in Primary Care-based Buprenorphine Treatment
Who cites it
184 citing papers in PubMed, 13 syntheses or guidelines pooled it, 423 citations in OpenAlex.
- Pooled it
- Interventions to safely and effectively reduce (taper) use of opioids in chronic non-cancer pain: a systematic review.Health technology assessment (Winchester, England) · 2026Pooled it
- Enhancing Chronic Non-Cancer Pain Management: A Systematic Review of Mindfulness Therapies and Guided Imagery Interventions.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Efficacy of interventions targeted at physician prescribers of opioids for chronic non-cancer pain: an overview of systematic reviews.BMC medicine · 2024Pooled it
- Resilience Interventions Conducted in Western and Eastern Countries-A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Mindfulness-based interventions for substance use disorders.The Cochrane database of systematic reviews · 2021Pooled it
- Deprescribing Opioids in Chronic Non-cancer Pain: Systematic Review of Randomised Trials.Drugs · 2020Pooled it
- Pooled it
- A meta-analysis of the effect of substance use interventions on emotion outcomes.Journal of consulting and clinical psychology · 2019Pooled it
- Brief Mindfulness-Based Interventions for Acute and Chronic Pain: A Systematic Review.Journal of alternative and complementary medicine (New York, N.Y.) · 2019Pooled it
- Interventions for the reduction of prescribed opioid use in chronic non-cancer pain.The Cochrane database of systematic reviews · 2017Pooled it
- Mindfulness Meditation for Chronic Pain: Systematic Review and Meta-analysis.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2017Pooled it
- Pooled it
- Feasibility and acceptability of skills training in affective recovery (STAR) video and TextSTAR text message program for recent sexual assault survivors.European journal of psychotraumatology · 2026Trial
- Skills Training in Affective Recovery Video and Text Programs for Recent Sexual Assault Survivors: A Pilot Randomized Clinical Trial.JAMA network open · 2026Trial
- Study Protocol for a Pain Self-Management Intervention to Reduce Pain and Improve MOUD Engagement in Primary Care: A Randomized Trial.Substance use & addiction journal · 2026Trial
- Participant Engagement With a Digital Behavioral Health App for Chronic Pain: Descriptive Secondary Analysis of a Feasibility Randomized Controlled Trial.JMIR human factors · 2026Trial
- Autonomic indices of negative emotion regulation predict treatment response in opioid-treated chronic low back pain.The journal of pain · 2026Trial
- Implicit opioid associations in OUD treatment: prediction of treatment response and moderation by mindfulness-oriented recovery enhancement.Psychological medicine · 2026Trial
- Mindful moms: acceptability and impact of co-designed and digitally delivered video meditations for pregnant and parenting women with opioid use disorder.Annals of medicine · 2025Trial
124 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 6 institutions in 2 countries.
Funding
Abstract
objectiveOpioid pharmacotherapy is now the leading treatment for chronic pain, a problem that affects nearly one third of the U.S. population. Given the dramatic rise in prescription opioid misuse and opioid-related mortality, novel behavioral interventions are needed. The purpose of this study was to conduct an early-stage randomized controlled trial of Mindfulness-Oriented Recovery Enhancement (MORE), a multimodal intervention designed to simultaneously target mechanisms underpinning chronic pain and opioid misuse.
methodChronic pain patients (N = 115; mean age = 48 ± 14 years; 68% female) were randomized to 8 weeks of MORE or a support group (SG). Outcomes were measured at pre- and posttreatment, and at 3-month follow-up. The Brief Pain Inventory was used to assess changes in pain severity and interference. Changes in opioid use disorder status were measured by the Current Opioid Misuse Measure. Desire for opioids, stress, nonreactivity, reinterpretation of pain sensations, and reappraisal were also evaluated.
resultsMORE participants reported significantly greater reductions in pain severity (p = .038) and interference (p = .003) than SG participants, which were maintained by 3-month follow-up and mediated by increased nonreactivity and reinterpretation of pain sensations. Compared with SG participants, participants in MORE evidenced significantly less stress arousal (p = .034) and desire for opioids (p = .027), and were significantly more likely to no longer meet criteria for opioid use disorder immediately following treatment (p = .05); however, these effects were not sustained at follow-up.
conclusionsFindings demonstrate preliminary feasibility and efficacy of MORE as a treatment for co-occurring prescription opioid misuse and chronic pain. (PsycINFO Database Record (c) 2014 APA, all rights reserved).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.