Evidence map›Paper›PMID 24490710›Full record

ArticleExperimental and clinical psychopharmacology2014

Craving as an alcohol use disorder symptom in DSM-5: an empirical examination in a treatment-seeking sample.

Cara M Murphy, Monika K Stojek, Lauren R Few, Alex O Rothbaum, James Mackillop

Abstract readValidation Study
In one paragraph

Article in Experimental and clinical psychopharmacology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Attentional Bias During a Novel Alcohol Cue Virtual Reality Paradigm.Alcohol, clinical & experimental research · 2026
    Article
  8. Observational
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Exacerbated Craving in the Presence of Stress and Drug Cues in Drug-Dependent Patients.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cara M MurphyDepartment of Psychology.
Monika K StojekDepartment of Psychology.
Lauren R FewDepartment of Psychology.
Alex O RothbaumDepartment of Psychology.
James MackillopDepartment of Psychology.

Funding

T32 Training Grant in Epidemiology, Services and Prevention ResearchT32DA007313 · NIDA · WASHINGTON UNIVERSITY · PI PRICE, RUMI KATO · 1999 to 2013
$2.9M
Enhancing Alcoholism Pharmacotherapy Research via Behavioral EconomicsK23AA016936 · NIAAA · UNIVERSITY OF GEORGIA · PI MACKILLOP, JAMES · 2008 to 2012
$805k
D-Cyloserine to Enhance Extinction to Alcohol CuesR21AA017696 · NIAAA · UNIVERSITY OF GEORGIA · PI MACKILLOP, JAMES · 2009 to 2010
$416k
NIAAA NIH HHS K23 AA016936NIAAA NIH HHS R21 AA017696NIAAA NIH HHS R21 AA017696-01A1NIDA NIH HHS T32 DA007313
6 · The paper itself

Abstract

Craving has been added as an alcohol use disorder (AUD) symptom in DSM-5 but relatively few nosological studies have directly examined the empirical basis for doing so. The current study investigated the validity of craving as an AUD symptom in a sample of heavy drinking treatment-seeking individuals. Using a semistructured clinical interview, individuals (N = 104; 62% male) were assessed for symptoms of DSM-IV AUD. The extent to which individuals endorsed pathological levels of craving in comparison with other AUD symptoms was investigated as was the association between craving and several aspects of problematic alcohol involvement. Factor analysis was utilized to examine whether craving and other AUD symptoms comprised a unidimensional syndrome. Results indicated that craving was significantly positively correlated with AUD severity, quantitative indices of drinking, and adverse consequences of alcohol abuse. In terms of frequency of endorsement, craving was present in 47% of the sample and was the 8th most frequent of the 12 symptoms evaluated. When considered with the DSM-IV AUD criteria, craving aggregated with other symptoms to form a unidimensional syndrome. Extending previous findings from epidemiological samples, these data suggest that, in a clinical sample, many relevant aspects of craving aggregate to form a diagnostic criterion that functions similarly to other AUD symptoms and is related to diverse aspects of alcohol-related impairment.

Indexed as

Diagnostic and Statistical Manual of Mental DisordersAdultAlcohol DrinkingAlcohol-Related DisordersData CollectionFactor Analysis, StatisticalFemaleHumansMaleMiddle AgedSeverity of Illness Index

Identifiers

PMID24490710
PMCPMC4105007

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.