Evidence map›Paper›PMID 24490096›Full record

ArticleCase reports in rheumatology2013

An atraumatic femoral fracture in a patient with rheumatoid arthritis and osteoporosis treated with denosumab.

J Villiers, D W Clark, T Jeswani, S Webster, A L Hepburn

Open access · goldAbstract read
In one paragraph

Article in Case reports in rheumatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Simultaneous bilateral atypical femoral fracture in a patient receiving denosumab: case report and literature review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016
    Review
  9. How Long to Treat with Denosumab.Current osteoporosis reports · 2015
    Review
  10. Article
  11. Atypical femoral fracture in a patient treated with denosumab.Journal of bone and mineral metabolism · 2015
    Article
  12. Review
  13. Applying low-intensity pulsed ultrasounds (LIPUS) to a zoledronate-associated atypical femoral shaft fracture without cessation of zoledronate therapy for 3 years follow up: a case report.Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

J VilliersDepartment of Rheumatology, Worthing Hospital, Worthing, UK.
D W ClarkDepartment of Orthopaedic Surgery, Worthing Hospital, Worthing, UK.
T JeswaniDepartment of Radiology, Worthing Hospital, Worthing, UK.
S WebsterDepartment of Rheumatology, Worthing Hospital, Worthing, UK.
A L HepburnDepartment of Rheumatology, Worthing Hospital, Worthing, UK.
Worthing Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoporosis is responsible for a significant burden both individually and socially, but is readily treated with antiresorptive agents and mineral supplementation. However, long-term usage of these agents, notably bisphosphonates, is rarely associated with atypical fractures. Denosumab is a monoclonal antibody that reduces osteoclast activity and thus increases bone mineral density. In this case report, we present a 78-year-old woman with a background of rheumatoid arthritis and osteoporosis who presented with an atypical diaphyseal femoral fracture.

Identifiers

PMID24490096
PMCPMC3893843
OpenAlexW2072109115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.