ArticleThe journal of physical chemistry letters2014
Quenching Dynamics of Ultraviolet-Light Perception by UVR8 Photoreceptor.
Article in The journal of physical chemistry letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed, 25 citations in OpenAlex.
- Dynamics and mechanism of dimer dissociation of photoreceptor UVR8.Nature communications · 2022Article
- Dynamics and mechanism of light harvesting in UV photoreceptor UVR8.Chemical science · 2020Article
- A leap in quantum efficiency through light harvesting in photoreceptor UVR8.Nature communications · 2020Article
- PET and FRET utility of an amino acid pair: tryptophan and 4-cyanotryptophan.Physical chemistry chemical physics : PCCP · 2019Article
- Q&A: How do plants sense and respond to UV-B radiation?BMC biology · 2015Article
- Two distinct domains of the UVR8 photoreceptor interact with COP1 to initiate UV-B signaling in Arabidopsis.The Plant cell · 2015Article
- On the mechanism of photoinduced dimer dissociation in the plant UVR8 photoreceptor.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Dynamic Crystallography Reveals Early Signalling Events in Ultraviolet Photoreceptor UVR8.Nature plantsArticle
- How Does Photoreceptor UVR8 Perceive a UV-B Signal?Photochemistry and photobiologyReview
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
UVR8 is a recently discovered UV-B photoreceptor with a homodimer as the active state. UV-B perception of an interfacial tryptophan (W285) causes dissociation of the dimer into two functional monomers. Here, we investigate the molecular mechanism behind UV perception by W285 in UVR8. We observed a significant quenching dynamics in about 150 ps within the interfacial four-tryptophan cluster and an unusual resonance energy transfer from the other ten tryptophans to the tryptophan cluster in 1-2 nanoseconds to enhance functional efficiency. With mutation of W285 to F, the quenching dynamics is highly suppressed in this intact mutant dimer and the overall fluorescence intensity dramatically increases by a factor of 6, indicating W285 as a dominant quencher. These results reveal a unique energy transfer mechanism for efficient UV perception and the critical functional role of W285 for primary quenching dynamics for initiating dimer dissociation to trigger the function.
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Registered trials
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