Trial reportOxidative medicine and cellular longevity2013
The effect of submaximal exercise preceded by single whole-body cryotherapy on the markers of oxidative stress and inflammation in blood of volleyball players.
Trial report in Oxidative medicine and cellular longevity, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Whole-body cryotherapy can reduce the inflammatory response in humans: a meta-analysis based on 11 randomized controlled trials.Scientific reports · 2025Pooled it
- Whole-Body Cryotherapy Increases the Activity of Nitric Oxide Synthase in Older Men.Biomolecules · 2021Trial
- Multiple Cryotherapy Attenuates Oxi-Inflammatory Response Following Skeletal Muscle Injury.International journal of environmental research and public health · 2020Trial
- Cold as a therapeutic frontier: place of whole-body cryotherapy in modern medicine.European journal of applied physiology · 2026Review
- Novel and emerging physical treatments for major depressive disorder.Fundamental research · 2025Review
- Effect of 2 weeks rest-pause on oxidative stress and inflammation in female basketball players.Scientific reports · 2024Article
- The Effect of Physical Activity and Repeated Whole-Body Cryotherapy on the Expression of Modulators of the Inflammatory Response in Mononuclear Blood Cells among Young Men.Journal of clinical medicine · 2024Article
- The Influence of Whole-Body Cryotherapy or Winter Swimming on the Activity of Antioxidant Enzymes.Biology · 2024Article
- The Influence of Single Whole-Body Cryostimulation on Cytokine Status and Oxidative Stress Biomarkers during Exhaustive Physical Effort: A Crossover Study.International journal of molecular sciences · 2023Article
- The Influence of Ambient Temperature Changes on the Indicators of Inflammation and Oxidative Damage in Blood after Submaximal Exercise.Antioxidants (Basel, Switzerland) · 2022Article
- Effect of Physical Exercise Under Different Intensity and Antioxidative Supplementation for Plasma Superoxide Dismutase in Healthy Adults: Systematic Review and Network Meta-Analysis.Frontiers in physiology · 2022Review
- Pre-Exercise Whole- or Partial-Body Cryotherapy Exposure to Improve Physical Performance: A Systematic Review.Sports (Basel, Switzerland) · 2021Review
- The Effect of Submaximal Exercise Followed by Short-Term Cold-Water Immersion on the Inflammatory State in Healthy Recreational Athletes: A Cross-Over Study.Journal of clinical medicine · 2021Article
- Cryostimulation for Post-exercise Recovery in Athletes: A Consensus and Position Paper.Frontiers in sports and active living · 2021Review
- The Effect of Repeated Whole-Body Cryotherapy on Sirt1 and Sirt3 Concentrations and Oxidative Status in Older and Young Men Performing Different Levels of Physical Activity.Antioxidants (Basel, Switzerland) · 2020Article
- Decreased Lipid Profile and Oxidative Stress in Healthy Subjects Who Underwent Whole-Body Cryotherapy in Closed Cryochamber with Subsequent Kinesiotherapy.Oxidative medicine and cellular longevity · 2019Article
- Whole body and partial body cryotherapies - lessons from human practice and possible application for horses.BMC veterinary research · 2018Review
- Article
- Thermal Sensations during a Partial-Body Cryostimulation Exposure in Elite Basketball Players.Journal of human kinetics · 2018Article
- Unchanged Erythrocyte Profile After Exposure to Cryogenic Temperatures in Elder Marathon Runners.Frontiers in physiology · 2018Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the study was to determine the effect of single whole-body cryotherapy (WBC) session applied prior to submaximal exercise on the activity of antioxidant enzymes, the concentration of lipid peroxidation products, total oxidative status, and the level of cytokines in blood of volleyball players. The study group consisted of 18 male professional volleyball players, who were subjected to extremely cold air (-130°C) prior to exercise performed on cycloergometer. Blood samples were taken five times: before WBC, after WBC procedure, after exercise preceded by cryotherapy (WBC exercise), and before and after exercise without WBC (control exercise). The activity of catalase statistically significantly increased after control exercise. Moreover, the activity of catalase and superoxide dismutase was lower after WBC exercise than after control exercise (P < 0.001). After WBC exercise, the level of IL-6 and IL-1β was also lower (P < 0.001) than after control exercise. The obtained results may suggest that cryotherapy prior to exercise may have some antioxidant and anti-inflammatory properties. The relations between the level of studied oxidative stress and inflammatory markers may testify to the contribution of reactive oxygen species in cytokines release into the blood system in response to exercise and WBC.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.