SynthesisPloS one2014
Laparoscopic versus open hepatectomy with or without synchronous colectomy for colorectal liver metastasis: a meta-analysis.
Synthesis in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02350166 (Short-term Effects of Laparoscopic-assisted Small-incision Surgery Versus Conventional Laparotomy in Treatment of Resectable Colorectal Liver Metastasis), which is not on this map. Cited by 22 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Short-term Effects of Laparoscopic-assisted Small-incision Surgery Versus Conventional Laparotomy in Treatment of Resectable Colorectal Liver Metastasis
Who cites it
22 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Laparoscopic versus open liver resection for colorectal liver metastasis: an umbrella review.Frontiers in oncology · 2024Pooled it
- Mini-invasiveWorld journal of gastroenterology · 2019Pooled it
- Laparoscopic Versus Open Liver Resection for Colorectal Liver Metastases: A Comprehensive Systematic Review and Meta-analysis.Scientific reports · 2017Pooled it
- Donor safety in live donor laparoscopic liver procurement: systematic review and meta-analysis.Surgical endoscopy · 2015Pooled it
- Outcomes of robotic vs laparoscopic hepatectomy: A systematic review and meta-analysis.World journal of gastroenterology · 2015Pooled it
- Subclinical Hypothyroidism and Type 2 Diabetes: A Systematic Review and Meta-Analysis.PloS one · 2015Pooled it
- Open versus minimally invasive liver surgery for colorectal liver metastases (LapOpHuva): a prospective randomized controlled trial.Surgical endoscopy · 2019Trial
- Emerging trends and outcomes in minimally invasive liver surgery: a population-based study in the Veneto region up to 2024 stratified by hospital case-volume.Updates in surgery · 2026Article
- Outcomes and Patient Selection in Laparoscopic vs. Open Liver Resection for HCC and Colorectal Cancer Liver Metastasis.Cancers · 2023Review
- Optimizing the Personalized Care for the Management of Rectal Cancer: A Consensus Statement.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2022Article
- Laparoscopic liver resection for colorectal liver metastases - short- and long-term outcomes: A systematic review.World journal of gastrointestinal oncology · 2021Article
- Current status of laparoscopic liver resection for the management of colorectal liver metastases.Journal of gastrointestinal oncology · 2020Review
- Long-Term and Oncologic Outcomes of Robotic Versus Laparoscopic Liver Resection for Metastatic Colorectal Cancer: A Multicenter, Propensity Score Matching Analysis.World journal of surgery · 2020Article
- The effect of antiviral therapy on patients with hepatitis B virus-related hepatocellular carcinoma after curative resection: a systematic review and meta-analysis.OncoTargets and therapy · 2017Article
- Laparoscopic hepatectomy versus open hepatectomy for colorectal cancer liver metastases: comparative study with propensity score matching.Hepatobiliary surgery and nutrition · 2016Article
- Laparoscopic simultaneous resection of colorectal primary tumor and liver metastases: a propensity score matching analysis.Surgical endoscopy · 2016Article
- Minimally Invasive Liver Surgery for Hepatic Colorectal Metastases.Current colorectal cancer reports · 2016Article
- Laparoscopic liver resection: Experience based guidelines.World journal of gastrointestinal surgery · 2016Review
- Laparoscopic surgery: A qualified systematic review.World journal of methodology · 2015Article
- Perspective of laparoscopic liver resection for hepatocellular carcinoma.World journal of gastrointestinal surgery · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo compare short-term and long-term results of colorectal patients undergoing laparoscopic and open hepatectomy. Moreover, outcomes of laparoscopic versus open procedures for simultaneous primary colorectal tumor and liver metastasis resection were compared.
methodsA systematic search was conducted in the PubMed and EmBase databases (until Oct. 22. 2013) with no limits. Bibliographic citation management software (EndNote X6) was used for extracted literature management. Quality assessment was performed according to a modification of the Newcastle-Ottawa Scale. The data were analyzed using Review Manager (Version 5.1), and sensitivity analysis was performed by sequentially omitting each study.
resultsFinally, 14 studies, including a total of 975 CLM (colorectal liver metastasis) patients, compared laparoscopic with open hepatectomy. 3 studies of them, including a total of 107 CLM patients, compared laparoscopic with open procedures for synchronous hepatectomy and colectomy. Laparoscopic hepatectomy was associated with a significantly less blood loss, shorter hospitalization time, and less operative transfusion rate. In addition, lower hospital morbidity rate (OR=0.57, 95%CI:0.42-0.78, P=0.0005) and better R0 resection (OR=2.44, 95%CI:1.21-4.94, P=0.01) were observed in laparoscopic hepatectomy. For long-term outcomes, there were no significant differences between two surgical procedures on recurrence and overall survival. In comparison of synchronous hepatectomy and colectomy, laparoscopic procedure displayed shorter hospitalization (MD = -3.40, 95%CI:-4.37-2.44, P<0.00001) than open procedure. Other outcomes, including surgical time, estimated blood loss, hospital morbidity, and overall survival did not differ significantly in the comparison.
conclusionsLaparoscopic hepatectomy with or without synchronous colectomy are acceptable for selective CLM patients. We suggest standard inclusion criteria of CLM patients be formulated.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.